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PECCAVI. The Latin word is scrawled in blood at the scene of a young woman's brutal murder: I HAVE SINNED. It's a chilling Christmas greeting for Boston medical examiner Maura Isles and Detective Jane Rizzoli, who swiftly link the victim to controversial celebrity psychiatrist Joyce O'Donnell, Jane's professional nemesis and member of a sinister cabal called the Mephisto Club.

In 2012, Nobel Prize winning scientist Jennifer Doudna hit upon an invention that will transform the future of the human race: an easy-to-use tool that can edit DNA. Known as CRISPR, it opened a brave new world of medical miracles and moral questions. It has already been deployed to cure deadly diseases, fight the coronavirus pandemic of 2020 and make inheritable changes in the genes of babies. But what does that mean for humanity?

French women don't get fat, but they do eat bread and pastry, drink wine, and regularly enjoy three-course meals. In her delightful tale, Mireille Guiliano unlocks the simple secrets of this "French paradox", how to enjoy food and stay slim and healthy. Hers is a charming, sensible, and powerfully life-affirming view of health and eating for our times.

Refusing to believe that she would be abandoned as a young child, Jenna searches for her mother regularly online and pores over the pages of Alice's old journals. A scientist who studied grief among elephants, Alice wrote mostly of her research among the animals she loved, yet Jenna hopes the entries will provide a clue to her mother’s whereabouts. Desperate to find the truth, Jenna enlists two unlikely allies in her quest.

Our lives are driven by a fact most of us can't name and don't understand: whether we're an introvert or an extrovert. This defines who our friends and lovers are, which careers we choose and whether we blush when we're embarrassed. At least a third of us are on the introverted side. Some of the world's most talented people are introverts. Without them, we wouldn't have the Apple computer, the theory of relativity and Van Gogh's sunflowers.

Siblings Without Rivalry guides the way to family peace and tranquility with humor and compassion for both parents and children. Action oriented and easy to understand, it's packed with sensitive yet sensible ways to turn quarreling siblings and frustrated parents into an open, communicative family.

The bestselling author of Leonardo da Vinci and Steve Jobs returns with a “compelling” (The Washington Post) account of how Nobel Prize winner Jennifer Doudna and her colleagues launched a revolution that will allow us to cure diseases, fend off viruses, and have healthier babies.

We used to think of failure as the opposite of success. Now, we’re often torn between two “failure cultures”: one that says to avoid failure at all costs, the other that says fail fast, fail often. The trouble is that both approaches lack the crucial distinctions to help us separate good failure from bad. As a result, we miss the opportunity to fail well.

At least one-third of the people we know are introverts. They are the ones who prefer listening to speaking; who innovate and create but dislike self-promotion; who favor working on their own over working in teams. It is to introverts—Rosa Parks, Chopin, Dr. Seuss, Steve Wozniak—that we owe many of the great contributions to society.

This edition brings together some of Ephron’s most famous writing on a generation of women (and men) who helped shape the way we live now, and on events ranging from the Watergate scandal to the Pillsbury Bake-Off. In these sharp, hilariously entertaining, and vividly observed pieces, Ephron illuminates an era with wicked honesty and insight. From the famous "A Few Words About Breasts" to important pieces on her time working for the New York Post and Gourmet Magazine, these essays show Ephron at her very best.

This is a fantastic first novel in a trilogy. Set in a parallel world, in an Italy that in this world is called Talia and in a Venice that in this world is called Bellezza, the narrative follows Lucien, who in this world is ill with cancer. Given a marbled notebook to help him communicate when his throat hurts too much to speak, this notebook is the means that transports Lucien to this magical, dangerous new world. This is a world which is set in the C16, and thrills to the delight of political intrigue, including assassination attempts both foiled and successful.

In 1963, a female student was attending a lecture given by Nobel Prize winner James Watson, then tenured at Harvard. At nineteen, she was struggling to define her future. She had given herself just ten years to fulfill her professional ambitions before starting the family she was expected to have. For women at that time, a future on the usual path of academic science was unimaginable—but during that lecture, young Nancy Hopkins fell in love with the promise of genetics. Confidently believing science to be a pure meritocracy, she embarked on a career.

Autumn Haven's Las Vegas "to-do" list said to catch a show and play the slots—not wake up married to a sexy jerk like Sam LeClaire. The first moment she saw him eyeing her like a luscious piece of the dessert buffet, her usually responsible self told her to run. And she did—right into the wildest fantasy weekend of her life. But Monday morning jolted her back to reality, and before she could say "pass the coffee", Sam was gone.

Told by a former high-level member of the Peoples Temple and Jonestown survivor, Seductive Poison is the "truly unforgettable" (Kirkus Reviews) story of how one woman was seduced by one of the most notorious cults in recent memory and how she found her way back to sanity.

A soaring bridge is an obvious infrastructural feat, but so are the mostly hidden reservoirs, transformers, sewers, cables, and pipes that deliver water, energy, and information to wherever we need it. When these systems work well, they hide in plain sight. Engineer and materials scientist Deb Chachra takes listeners on a fascinating tour of these essential utilities, revealing how they work, what it takes to keep them running, just how much we rely on them—but also whom they work well for, and who pays the costs.

What do you do when you are a nanny to an obscenely rich Park Avenue matron named X? Mrs. X refuses to do anything for herself, including cook, clean, or take care of her 4-year-old son. You are expected to do everything, including maintaining the mental health of said 4-year-old, even while Mrs. X decides that it is time for a divorce. You'll have to bear up under the strain with wit and panache, even as the boundaries between your working life and your so-called private life blur, merge, and disappear.

Harvard Professor Amy Edmondson has spent four decades arguing that productive failure hold the key to lasting success. The world's leading expert on psychological safety, her research has shown that the most successful environments are those in which we can fail effectively - without our mistakes being held against us. Now, Edmondson offers a revolutionary framework to get these failures right. She outlines the three archetypes of failure - simple, complex, and intelligent - before revealing how to minimise the consequences of the bad failures and maximise the potential of the good.

West Hall, Vermont, has always been a town of strange disappearances and old legends. The most mysterious is that of Sara Harrison Shea, who, in 1908, was found dead in the field behind her house just months after the tragic death of her daughter, Gertie. Now, in present day, 19-year-old Ruthie lives in Sara's farmhouse with her mother, Alice, and her younger sister, Fawn. Alice has always insisted that they live off the grid, a decision that suddenly proves perilous when Ruthie wakes up one morning to find that Alice has vanished without a trace. Searching for clues, she is startled to find a copy of Sara Harrison Shea's diary....

Returning home from a trip to Paris, Boston medical examiner Maura Isles confronts a nightmarish scene. Police cruisers line her street and slumped in a car at the end of Maura's driveway is a dead woman, her head bloodied by a gunshot wound. Cops and neighbors gape at her as she approaches. Only when Maura looks at the victim does she understand why everyone is so shocked by her arrival. The dead woman looks exactly like Maura.

In The Best American Erotica 2002, Maggie Estep relates the surprising sexual happenings in a detox clinic, Francesca Lia Block explores the aquatic fantasies haunting a surfer, and Ernie Conrick introduces a tennis star and sex symbol who surrenders to an unusual coach. In these 23 stories you will also find cutting-edge work from other luminaries and from the Internet, where the next wave of erotica has matured into some of the most enticing writing around.