The Code Breaker Titelbild

The Code Breaker

Jennifer Doudna, Gene Editing, and the Future of the Human Race

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The Code Breaker

Von: Walter Isaacson, Walter Isaacson - introduction
Gesprochen von: Kathe Mazur
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Über diesen Titel

 A 2022 Audie Award Finalist

A Best Book of 2021 by Bloomberg BusinessWeek, Time, and The Washington Post

The bestselling author of Leonardo da Vinci and Steve Jobs returns with a “compelling” (The Washington Post) account of how Nobel Prize winner Jennifer Doudna and her colleagues launched a revolution that will allow us to cure diseases, fend off viruses, and have healthier babies.

When Jennifer Doudna was in sixth grade, she came home one day to find that her dad had left a paperback titled The Double Helix on her bed. She put it aside, thinking it was one of those detective tales she loved. When she read it on a rainy Saturday, she discovered she was right, in a way. As she sped through the pages, she became enthralled by the intense drama behind the competition to discover the code of life. Even though her high school counselor told her girls didn’t become scientists, she decided she would.

Driven by a passion to understand how nature works and to turn discoveries into inventions, she would help to make what the book’s author, James Watson, told her was the most important biological advance since his codiscovery of the structure of DNA. She and her collaborators turned a curiosity of nature into an invention that will transform the human race: an easy-to-use tool that can edit DNA. Known as CRISPR, it opened a brave new world of medical miracles and moral questions.

The development of CRISPR and the race to create vaccines for coronavirus will hasten our transition to the next great innovation revolution. The past half-century has been a digital age, based on the microchip, computer, and internet. Now we are entering a life-science revolution. Children who study digital coding will be joined by those who study genetic code.

Should we use our new evolution-hacking powers to make us less susceptible to viruses? What a wonderful boon that would be! And what about preventing depression? Hmmm…Should we allow parents, if they can afford it, to enhance the height or muscles or IQ of their kids?

After helping to discover CRISPR, Doudna became a leader in wrestling with these moral issues and, with her collaborator Emmanuelle Charpentier, won the Nobel Prize in 2020. Her story is an “enthralling detective story” (Oprah Daily) that involves the most profound wonders of nature, from the origins of life to the future of our species. Akademiker & Spezialisten Frauen Wissenschaft Wissenschaft & Technik

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Kritikerstimmen

"Kathe Mazur skillfully narrates this clear and well-researched biography of Nobel Prize winner Jennifer Doudna, who, along with colleagues, advanced biochemistry by employing CRISPR technology to improve and simplify genetic engineering—ultimately leading to a safe, effective COVID vaccine. Moving beyond Doudna's own story, this audiobook also discusses the role of women in science, the intersection of research and business, competitiveness (and cooperation) in academia, and the implications of altering human genes. Mazur's personable delivery and measured pace help listeners access the science and connect to Doudna as a woman and a researcher. Her performance highlights the excitement of new discoveries, the difficulties of forging new paths, the wide-ranging ethical concerns of emerging technologies, and the hope for humanity's future. Author Walter Isaacson reads the epilogue."
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I mostly liked the book, but it also it some boring and repetitive notes and extremely common and prevalent political points typical for our times.
The book had long and tordeous chapters on the ethical questions concerning CRISPR technology, yet the only useful sentence was one mentioning Steven Pinker's opinion in the Boston Globe, urging so-called bioethicists 'to get out of the way'. Having read that comment kind of annulled all the book's many musings.

Interesting story of our times' biogeneticists

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I really enjoyed the book but I think it would have been better without the focus on doudna. It is clear that this has been a team effort at every step and the author makes this clear as well, so I don't really understand the focus on her. still thoroughly recommended.

interesting story about an important topic

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Was ist mit Gentechnik bisher erreicht worden, wer hat das wie gemacht und wo geht die Reise hin? Wer hierfür interessiert ist und kein Impfgegner ist, ist hier richtig.

Nichts für Querdenker

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I have enjoyed every minute of listening to this audiobook. It gives an interesting and understandable overview of the current developments in molecular biology. It is meanwhile my third book from Walter Isaacson who is becoming one of my favorite authors.

Fascinating!

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Is pushing me to study biotechnology. great book, but was kind expecting that from this author.

Just wow!!

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A fascinating book,Walter Isaacson understands to present a highly complex theme in a very structured and understandable way.it is additionally enriched with many very personal and emotional elements.A masterpiece!

Brillant

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No prior knowledge required. Well written. After you’ve read this, you’ll have a good idea about the subject.

Will bring you up to date on genetic engineering

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It is obvious that Mr Isaacson has understood a great deal about this new technology. It is also obvious that he is a very adept storyteller.
But the struggle to combine knowledge and story into a book, which nearly everybody could read is at times, even for him challenging. The fluctuation of scientific depth and anecdotal evidence sometimes was difficult to follow.
But in general, it was a perfect overview into how old this new field of biotechnology can open up our world into a new way of understanding who we are. It is a great trigger to contemplate life and the possibilities our time brings with it.

An introduction to the future of life sciences

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I read four other books by Isaacson and loved him as an insightful and neutral observer. This book is different. The whole book is a public relations package for the main character. He is bending over backwards to justify an obviously greedy, self centered and competitive management character.

This book makes me sad

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As a scientist, I found it a bit tedious the very first half. It got better by the last chapters though.

Gets better by the last chapters

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