England, 1941. After three nights of relentless bombing from German aircraft, trained nurse Jo Brooks is told to report to the basement theater of Mill Road Hospital. She goes with a heavy heart, not wanting to leave behind her best friend Moira, who is desperately soothing new mothers on the maternity ward. As Jo arrives safely underground, the ward takes a direct hit. 

1942, New York. As war rages in Europe, Lily Rose is grateful for her perfect life: a wealthy family who love her and a dream job working uptown as a restaurant chef. Times are changing for women, and Lily is determined to run her own kitchen one day. She hopes handsome Tom Morelli, son of Sicilian immigrants, will be at her side. Together they work late, dreaming up delicious meals for New Yorkers struggling with wartime rationing and the threat of sons and sweethearts being called up. Then Tom receives a devastating telegram that changes everything: He is drafted to fight in Italy.

Hull, 1940. Widowed Edie Copeland has just arrived on Exchange Street, heavily pregnant and with heavy suitcase in tow. She left York after tragedy struck to make a fresh start, but she's a stranger to this street, and her new landlord doesn't hesitate to remind her of this, widow or not. Luckily, the neighbours are a little more welcoming and Edie is soon made to feel at home by the Maguires and the Scuttles. As air raids sound and the war feels closer than ever, the community has to stick together. But Edie is hiding something, and she doesn't know how much longer her secret is safe.

Liverpool, 1855. Ada Houston is alone. Her grandfather has recently passed away, and her brother is missing, last seen working on the Liverpool docks. Everyone assumes him to be dead. But she will not give up hope. Ada's determined search takes her to the Crimea, where she joins the team of Florence Nightingale's nurses. She may have set off looking for her brother, but along the way Ada finds friends, romance and a new purpose in her own life in the most troubling and difficult of places.

Liverpool, 1868. Shrouded in secrecy, Alice Sampson gives birth to a beautiful baby girl. But the former nurse's happiness is blighted by the knowledge that as a penniless, unwed mother, her future, and that of her child, can only be one of shame and disgrace. Then a knock at the door brings a miracle: she is invited to return to the Liverpool Royal Infirmary and her beloved ward. With the help of her friends and the welcome attentions of Reverend Seed, the hospital Chaplain, Alice slowly starts to rebuild her life. 

Brussels, April 1915. A beautiful young woman finds herself on the run from the enemy. Also being pursued is Ned Scott, a British army major who has been badly injured. The pair find themselves at a hospital run by the famous Edith Cavell, who agrees to treat the major while offering them both refuge and a false identity - she names the young girl Anna. 

Life is tough for Ella Bancroft. After her father, Thomas, is wheelchair-bound by an accident at the tube works, the responsibility for keeping a roof over their head falls to Ella. Ella’s mother died when she was 10, and her sister, Sally, lives with her no-good, work-shy husband Eddy, so is no help at all. If she and her father are to keep the bailiffs from the door, then Ella must earn a living. But Ella is resourceful as well as creative and soon discovers she has a gift for millinery.

September 1939. As Britain is gripped by the fear and uncertainty of war, Tom Armitage stands to gain the one thing that he never thought possible - his freedom. Rosie Elliot sees her future crumbling to dust as Will Aarons leaves Whitby with Jimmy Chappell to fight in the war. As she begins work at The Turnstone Convalescent Home, Rosie finds something she thought she had lost. Friendship.

1944, London. When Lily meets enigmatic GI Matthew in war-torn London, she doesn’t expect to fall in love. While her sister starts a reckless affair with another GI, Lily tries to hide her growing feelings for Matthew. But Matthew has a devastating secret. One that could change their lives forever.

Bristol, 1939. School leaver Maisie Miles suspects her father, a small-time crook, has an ulterior motive for insisting she gets a job at the W. D. & H. O. Wills tobacco factory but keeps it to herself. She's befriended by effervescent Phyllis Mason and kind-hearted Bridget Milligan who take pity on her and take Maisie under their wing. But beneath their happy-go-lucky exteriors, they all harbour dreams and worries about what the future holds.