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In this irreverent and illuminating popular science show, award-winning geneticist Dr Adam Rutherford teams up with mathematics guru Dr Hannah Fry to solve puzzling conundrums sent in by listeners. For the past five years, they've been scrutinising a cornucopia of cases using the power of science - from why people shout on their mobile phones to how much the bacteria in our body weighs. In these 50 episodes, they tackle topics including what makes gingers ginger, how to make the perfect cup of tea, whether being left-handed affects your brain and why we get static shocks.

Why did almost all life go extinct 250 million years ago? Why on five other occasions in the geological history has the living world experienced sudden episodes of global mega-death with the majority of species being annihilated? And are humans causing the sixth great mass extinction event in Earth's history? These are among the questions Adam Rutherford explores in this three-part series on extinction. Producer: Andrew Luck-Baker.

These 29 episodes encompass classic cosmic conundrums - including whether there is intelligent alien life out there, if infinity exists and how wormholes could allow us to time-travel - as well as probing more down-to-earth human quirks like our differing pain thresholds, our attraction to 'bad' foods like chips and chocolate and our varied regional accents. Plus, the duo embarks on a cheery evolutionary thought experiment as they wonder what would happen if humanity became extinct....

Geneticist Adam Rutherford and mathematician Hannah Fry guide listeners through time and space, through our bodies and brains, showing how emotions shape our view of reality, how our minds tell us lies, and why a mostly bald and curious ape decided to begin poking at the fabric of the universe.

What is life? Humans have been asking this question for thousands of years. But as technology has advanced and our understanding of biology has deepened, the answer has evolved. For decades, scientists have been exploring the limits of nature by modifying and manipulating DNA, cells, and whole organisms to create new ones that could never have previously existed on their own.