🎙️ CIC 2024: NACI, Real World Evidence and Pharmacoeconomic Modeling with Dr. Jesse Papenburg 🎙️

We sit down with dynamic public health leader and clinician scientist Dr. Jesse Papenburg—a member of the National Advisory Committee on Immunization (NACI) and the Quebec Immunization Committee, where he leads the influenza and RSV working groups, respectively, and the voice behind some of the latest vaccine recommendations 💉.

We unpack the science behind high-dose, adjuvanted, and recombinant influenza vaccines 🧬🩺, specifically tailored for adults 65+. Discover how these specialized vaccines offer enhanced protection by boosting immune responses where it counts the most 🚀💪.

Dr. Jesse Papenburg also sheds light on the groundbreaking RSV vaccines designed to shield older adults from severe respiratory illnesses 🤧🛡️

• With behind the scenes insights into how cost-effectiveness, real-world efficacy, and economic modeling factor behind NACI's recommendations 📊💡, this episode delivers both the technical deep dive and the human touch that brings public health to life ❤️.

And for a refreshing twist, learn about Jesse Papenburg's off-duty passion 😎🥏.

Learning Objectives:

1. Decipher the Vaccine Jargon:
   Understand why high-dose, adjuvanted, and recombinant influenza vaccines are revolutionizing protection for adults 65+ and 75+ 🕵️‍♂️💉.
2. RSV Revealed:
   Gain insight into the new RSV vaccines for seniors, how they reduce the risk of severe respiratory infections, and why they're becoming a critical tool in our public health arsenal 🛡️📊.
3. Risk Factors & Real Talk:
   Explore how age, comorbidities, and living environments like long-term care facilities amplify risks—and why personalized vaccine strategies are essential in today’s healthcare landscape 🏥🔍.
4. Tech Talk + Public Health:
   Delve into the emerging role of AI and predictive modeling in shaping future vaccination policies, offering a fresh perspective on how data-driven insights are changing the game 🤖🚀
5. NACI's Art of Decision Making:
   Behind the scenes insights into how cost-effectiveness, real-world efficacy, and economic modeling factor behind NACI's recommendations 📊💡

Whether you're a healthcare provider seeking the latest evidence-based updates or a public health policy buff, this episode promises a perfect blend of scientific rigor, practical insights, and a dash of fun! 🎧✨

Dr. Jesse Papenburg practices Pediatric Infectious Diseases and Medical Microbiology at the Montreal Children’s Hospital of the McGill University Health Centre.

After his specialty training, Dr. Papenburg completed a research fellowship on the molecular virology of RNA respiratory viruses at Laval University and an MSc in epidemiology at McGill. As a clinician scientist, he studies the epidemiology of viral respiratory infections. Dr. Papenburg is a member of the National Advisory Committee on Immunization and the Quebec Immunization Committee where he leads the influenza and RSV working groups, respectively.

🍞🥖💉Ever heard of a sourdough geek who also happens to be a rockstar vaccine expert? Join host 🤓 Dr. Carolyn Quash on the Find My Vaccine Podcast as she kneads out the details with immunization guru

🏅 Dr. Caroline Quach—fresh from Quebec 🍁 and fresh out of flour! From sprinkling dough across her kitchen (sorry, husband!) to sprinkling wisdom on immunocompromised patient care 🏥🛡, Dr. Quach dishes on how precision vaccinology 💡, AI-driven modeling 🤖, and big-data insights 📊 are stirring up a brand-new recipe for public health guidance. Get ready to rise to the occasion—and maybe rise some bread on the side! 🍞🔥

Learning Objectives 🎯

1. Sourdough & Science 🥖🔬: Understand how baking bread (yes, really!) parallels the trial-and-error approach in developing vaccination recommendations.
2. Immunocompromised Insights 💊🤝: Learn the biggest challenges (and breakthroughs) in vaccinating special patient populations—especially those under biologics or CAR T-cell therapies.
3. Modeling & More 🤖🔎: Discover how in silico trials, predictive modeling, and AI might shape tomorrow’s vaccination schedules.
4. Policy in Action 🏛⚖️: Grasp the role of NACI in translating groundbreaking research into real-world immunization guidance.

Don’t miss this chance ⏰ to raise your knowledge, feed your curiosity, and find the perfect recipe for innovative vaccine strategies! Tune in now, and let’s get kneading! 🥖🎙️💉

Dr. Caroline Quach is a Professor in the Departments of Microbiology, Infectious Diseases & Immunology and of Pediatrics at University of Montreal. She is an adjunct Professor in the Department of Epidemiology, Biostatistics & Occupational Health at McGill University and a scientific collaborator at the School of Public Health at Université Libre de Bruxelles (ULB) in Brussels. She is the physician in charge of Infection Prevention and control at CHU Sainte-Justine where she also works as a pediatric infectious diseases specialist and medical microbiologist. Dr. Quach is a clinician-scientist, supported by the Fonds de Recherche Québec – Santé (FRQS, chercheure boursière de mérite) and was recently awarded the Canada Research Chair, Tier 1 in Infection Prevention and Control. Her research interests are in Infection Prevention: both healthcare-associated and vaccine-preventable diseases.

Dr. Quach is the former Chair of the National Advisory Committee on Immunization (NACI )from the Public Health Agency of Canada. She is a former president from the Association for Medical Microbiology and Infectious Diseases (AMMI) Canada (2014-2016). She was named Fellow of the Canadian Academy of Health Sciences and of the Society for Healthcare Epidemiology of America. Dr. Quach was selected as one of the 2019 most Powerful Women in Canada (2019 Top 100 Award Winner in the Manulife Science and Technology category).

🎙️FindMyVaccine is back with infectious diseases physician, Dr. Zain Chagla, who joins us from Toronto in studio.

As we head into Fall 2024, it's not just the leaves changing-we cover the latest updates on COVID-19, new variants, new boosters, and new messaging we head into respiratory season. 🦠

In this episode, we cut through the noise and dive into what you need to know.

❓ Why is this surge happening again? We'll look at the data from this past summer's outbreaks and discuss why it's crucial to stay on top of this evolving situation.

🛡️ Booster blues? Vaccine uptake is still low among at-risk populations, and there's a new booster in town. But how do you communicate that effectively to patients without sounding like a broken record—or worse, adding to the confusion?

💡Navigating patient conversations around booster recommendations 🛑 and why the message has shifted. Get practical tips for identifying high-risk patients and translating NACI recommendations into action. It's not just about age; it's about timing, awareness, and making sure your patients understand why the next dose matters.

📅 Plus, we discuss how to prioritize COVID vs. flu vaccines.

🎧 Tune in for the latest on COVID, and more, with expert insights and a touch of humor.

• COVID Surge Alert: Hospitalizations and test positivity are up again 🦠📈
• Vaccine Timing: Why it’s crucial to get your COVID shot now, with flu and RSV lurking around the corner. 🎯💉
• Cross-Neutralization Explained: How the new COVID variants differ and why updated vaccines still provide protection. 🧬🛡️
• COVID Therapeutics: Paxlovid effectiveness in the context of new variants🏃‍♂️📅
• Patient Conversations: Strategies for helping patients understand their risks and prioritize getting vaccinated. 🗣️👩‍⚕️

Dr.Zain Chagla, MD MSc MD, FRCPC is an associate professor at McMaster University, co-medical director of infection control at St. Joseph’s Healthcare Hamilton and a consultant in infection control at Woodstock General Hospital. Dr. Chagla is also a teacher at McMaster University where he won a clinician teaching award in internal medicine and a young investigator grant for his work in supporting undergraduate medical education at the University of Namibia.

Dr. Chagla also has a Master of Science in infectious diseases and a diploma in tropical medicine and hygiene from the London School of Hygiene & Tropical Medicine.

As an infectious disease specialist, Dr.Zain Chagla has given media interviews on the COVID-19 pandemic and published several op-eds on testing, disease elimination, and public health interventions. He has contributed to local, provincial, and federal policy planning, and to several clinical trials on COVID-19 therapies. He has published works on COVID-19 research, epidemiology, testing, and infection control. He is involved with a prospective cohort study looking at respiratory physiology and radiologic features of patients post covid with persistent symptoms over time, including those with long covid and those who were critically ill.