Join us for a fascinating conversation with Dr. Chad Pozarycki, PhD in analytical chemistry and astrobiology, as we dive into the cutting-edge science behind searching for life beyond Earth. In this episode, we explore groundbreaking research on how biosignature molecules—such as amino acids and ATP—can accumulate and persist in extreme, hypersaline brine environments analogous to those found on Mars, Europa, and other planets.Dr. Pozarycki explains the unique analytical challenges of working with highly salty samples, discusses innovative techniques like capillary electrophoresis and high-resolution mass spectrometry, and offers key advice for scientists developing the next generation of space-ready instruments. If you’re curious about how planetary scientists actually analyze samples from Mars or icy moons, or are interested in the intersection of analytical chemistry, planetary exploration, and astrobiology, this episode is for you!🔬 Topics covered:- Analytical methods for detecting biomolecules in salt-rich planetary environments- Overcoming salt-interference in chromatography and mass spectrometry- Method validation in extreme conditions- Adapting scientific instruments for use on Mars rovers and Europa landers- Career and practical advice for aspiring analytical chemists and astrobiologistsDon’t miss Dr. Pozarycki’s insights on the next frontiers for miniaturized analytical instruments and what it takes to prepare for future space missions.Listen now to discover how planetary analog research on Earth paves the way for discovering life elsewhere in our solar system!#Astrobiology #AnalyticalChemistry #SpaceExploration #PlanetaryScience #Chromatography #MassSpectrometry #Biosignatures

🧪 Transform Your Understanding of Modern Chromatography & AI!

Join us for an eye-opening conversation with Professor Dwight Stoll from Gustavus Adolphus College as he reveals how his team is revolutionizing liquid chromatography through high-throughput data collection and machine learning. With over 43,000 retention measurements and groundbreaking research spanning three major publications, Prof. Stoll is pioneering the future of analytical chemistry.🔬 What You'll Learn:- How short columns (5mm vs 100mm) dramatically increase measurement throughput while maintaining accuracy- The evolution from HSM1 to HSM3 models and their predictive capabilities - Why selectivity ratios are more stable than absolute retention factors- The "Manhattan Project of Chromatography" - building massive retention databases- Key challenges: column drift, mobile phase standardization, and precision trade-offs- Career advice for researchers at the intersection of chromatography and data science📊 Key Highlights:- 43,329 total retention measurements across 13 stationary phases- Revolutionary "feed injection" method for high-throughput analysis- Improved isomer selectivity predictions - crucial for pharmaceutical analysis- The holy grail: predicting retention from molecular structures🎯 Perfect For:- Analytical chemists and chromatographers- Data scientists interested in chemistry applications- Graduate students and researchers- Pharmaceutical industry professionals- Anyone curious about AI applications in science🔗 Connect with Prof. Stoll:- Gustavus Adolphus College Chemistry Department- Research focused on liquid chromatography and 2D-LC#Chromatography #MachineLearning #AnalyticalChemistry #AI #DataScience #Research #HPLC #Pharmaceutical #Chemistry #ScienceThis interview showcases cutting-edge research that's transforming how we approach method development in liquid chromatography. Don't miss this glimpse into the future of analytical chemistry!

Join David Oliva on the Concentrating on Chromatography podcast as he interviews Edward Faden, Vice President and co-owner of MAC-MOD Analytical, a leading provider of chromatography solutions since 1986. In this insightful discussion, Edward shares the history and expertise of MAC-MOD, based in Chadds Ford, Pennsylvania, and dives deep into the critical challenges of analyzing PFAS (per- and polyfluoroalkyl substances), often called "forever chemicals."Key topics include:- The pervasive nature of PFAS contamination in both environmental and laboratory settings.- Surprising sources of PFAS contamination identified in standard lab setups, from gas line tubing to everyday consumables.- The essential role of the PFAS Delay Column in ensuring accurate analysis by minimizing background interference.- Best practices for labs starting PFAS analysis to reduce contamination risks from day one.- Exciting developments in rapid sample pre-screening methods to prevent cross-contamination.Edward also discusses why PFAS are so widespread—used in products like non-stick cookware and waterproof clothing since the 1940s—and the ongoing struggle to manage their environmental persistence. Whether you're a chemist, environmental scientist, or simply curious about the impact of forever chemicals, this conversation offers valuable insights into cutting-edge analytical solutions.Don't miss out on learning about MAC-MOD's innovative approaches and future plans for PFAS analysis. Subscribe for more expert interviews and chromatography content!#Chromatography #PFAS #ForeverChemicals #EnvironmentalScience #LabAnalysis