It’s 1965, and life has taken a turn for eighteen-year-old Anton Addison-Rice. Nearly a year after his brother died in a tragic accident, Anton is still wounded - physically and emotionally. Alone for the holidays, he catches a glimpse of his neighbor Edith across the street one evening and realizes that she’s in danger. Anton is determined to help Edith leave her abusive marriage. Frightened and fifteen years Anton’s senior, Edith is slow to trust. But when she needs a safe place to stay, she lets down her guard, and over the course of ten days an unlikely friendship grows.

For five years Pearl has managed to keep the past from catching up to her and her bright, frail five-year-old son. Life has given her every reason to mistrust people, but circumstances force her to trust her neighbor Mitch with watching Leonard while she goes off to work. Then one day Pearl drops her son off, and never returns.

Sebastian, a lonely 17-year-old, is suffocating under his dominant father's control. In the 10 years since his mother passed away, his father has kept him "safe" by barely allowing him out of their apartment. Sebastian's secret late-night subway rides are rare acts of rebellion.

Something has been asleep in forty-year-old cattle rancher Aiden Delacorte for a long time. It all comes back in a rush during a hunting trip, when he's suddenly attuned to the animals around him, feeling their pain and fear as if it were his own. But the newfound sensitivity of Aiden's "wake up" has its price. He can no longer sleepwalk through life, holding everyone at arm's length. As he struggles to cope with a trait he's buried since childhood, Aiden falls in love with Gwen, a single mother whose young son bears a burden of his own.

Brooke is a divorced single mom, financially strapped, living with her mother, and holding tight to the one thing that matters most: her two-year-old daughter, Etta. Then, in a matter of seconds, Brooke’s life is shattered when she’s carjacked. Helpless and terrified, all Brooke can do is watch as Etta, still strapped in her seat, disappears into the Los Angeles night. Miles away, Etta is found by Molly, a homeless teen who is all too used to darkness. Thrown away by her parents, and with a future as stable as the wooden crate she calls home, Molly survives day to day by her wits.

Roseanna Chaldecott spent her life as a high-powered lawyer in Manhattan. But when her best friend and law partner dies suddenly, something snaps. Unsure of her future, Roseanna heads upstate on one tank of gas and with no plans to return. In the foothills of the Adirondacks, Roseanna discovers the perfect hideout in a ramshackle farm. Its seventy-six acres are rich with possibilities and full of surprises, including a mother and daughter squatting on the property. Although company is the last thing Roseanna wants, she reluctantly lets them stay.

On an isolated Texas ranch, Dr. Lucy cares for abandoned animals. The solitude allows her to avoid the people and places that remind her of the past. Not that any of the townsfolk care. In 1959, no one is interested in a woman doctor. Nor are they welcoming Calvin and Justin Bell, a newly arrived African American father and son.

Michael Steeb is an aimless 21-year-old pot farmer in Central California in the 1980s. He has no real plans or interests...until the day he connects with memories of a life that seems to belong to someone else. That "spirit" is Walter, a young American soldier killed in World War II. Michael's task is the near-impossible: to lead Walter's family to closure and peace, to deliver the real truth behind Walter's Purple Heart, and to somehow achieve the forgiveness absent for so many years so Walter can move on.

Vida is only 19, but she knows a lot about dying. Her weak heart has kept her on the edge of death her whole life. It hasn't been much of a life. Thanks to her overprotective mother, Vida's only friend is Esther, an elderly Holocaust survivor who lives upstairs. Vida's heart is finally about to give out unless she can get a donor heart in time. Richard is 36 and blissfully married until he gets the call that his beloved wife has died in a car accident. His world falls to pieces.

Bea has barely been scraping by since her husband died. After falling for a telephone scam, she loses everything and is forced to abandon her trailer. With only two-thirds of a tank in her old van, she heads toward the Pacific Ocean with her cat - on a mission to reclaim what's rightfully hers, even if it means making others pay for what she lost.