The galaxy is in flames. Chaos is in the ascendant across the stars. The Great Rift has split the holdings of the Imperium in twain, isolating entire sectors from the light of Holy Terra. But all hope is not lost. The Primarch Roboute Guilliman has returned from deathless sleep and appointed Commander Dante, lord of the Blood Angels, as Regent and Warden of the newly dubbed Imperium Nihilus. In the Baal system, the shattered holding of the Chapter is being rebuilt, and Dante plans the greatest campaign of his long life, to retake half an empire. 

On the war-torn world of Armageddon, Gabriel Seth and his Flesh Tearers accompany an Imperial inquisitor and her retinue on a mission of vital importance. But the inquisitor has a hidden agenda that could imperil not only Seth's mission but the very existence of his Chapter...unless he takes drastic action.

In the city of Queen Mab, nothing is quite as it seems. Pariah, spy and Inquisitorial agent Alizebeth Bequin is all of these things and yet none of them. An enigma, even to herself, she is caught between Inquisitors Gregor Eisenhorn and Gideon Ravenor, former allies now enemies who are playing a shadow game against a mysterious and deadly foe. Coveted by the archenemy, pursued by the Inquisition, Bequin becomes embroiled in a dark plot of which she knows not her role or purpose.

In the aftermath of battle, Flesh Tearers Chapter Master Amit picks his way across the blasted landscape and is drawn into single combat with a survivor of the enemy force, a berserker dedicated to the Blood God. As they fight, Amit begins to realise that at slaughter's end, he and the servant of Khorne are not so dissimilar.

In the mysterious city of Queen Mab, the forces of light and darkness are locked in a murderous struggle for truth. The dedicated agents of the Holy Inquisition battle with their shadowy counterparts, the infamous Cognitae, to discover the encrypted identity of the enigmatic, all-powerful King in Yellow. Caught at the heart of this struggle is the pariah Alizebeth Bequin. Bequin must withstand an onslaught of angels, daemons, and even the monstrous warriors of the Traitor Legions, to unpick the greatest riddle of her life. 

In the darkness beyond the galaxy, there are monsters. Some swim closer to the light, drawn by the beacon that is the Astronomican, while others stalk the Void, predators in the dark. The Carcharodons have hunted for millennia, but now they are drawn into a new blackness...the Dark City of the drukhari itself. Commorragh. For a thousand years, Chaplain Tangata Manu has searched for a relic lost under his watch: an ancient thing, once charged into the keeping of the Forgotten One himself. But at the brink of seeing his hunt fulfilled and the relic returned, it is stolen from under him.

As the Indomitus Crusade begins, fleets of mighty warships leave Terra on a vital quest to stabilise Imperium Sanctus in the wake of the Great Rift. The returned primarch, Roboute Guilliman, leads a huge force towards the shrine world of Gathalamor, where stable warp routes will allow the flotilla to spread across the beleaguered southern half of the Imperium.

When the world of Armageddon is attacked by orks, the Black Templars Space Marine Chapter are amongst those sent to liberate it. Chaplain Grimaldus and a band of Black Templars are charged with the defence of Hive Helsreach from the xenos invaders in one of the many battle zones. But as the orks' numbers grow and the Space Marines' numbers dwindle, Grimaldus faces a desperate last stand in an Imperial temple.

Of all the Emperor’s sons who fell to Chaos, it is perhaps Magnus the Red whose tale is the most tragic. Sanctioned because of his desire for knowledge, chastised, judged, and shattered to his very elements – there is much for the Crimson King to feel vengeful for. Yet revenge is not the only thing that draws him to Terra alongside the Warmaster’s besieging armies. He seeks something, a fragment, the missing piece of himself that lies within the most impregnable place on the planet – the inner sanctum of the Imperial Palace.

After a series of victories, the Imperial forces are on the back foot once more. The power of Chaos is rising, the Traitors gain ground, and all hope seems lost. Can Terra endure?