If you are in the midst of depression, you may worry that you aren't good enough for your partner, or become irritable around them. You may even push them away when you feel like your emotions are beyond your control. In addition, your sense of intimacy may diminish, and your sex life may fizzle as a result of fatigue, medications and feeling disconnected from your partner. The hard truth is that feelings of isolation, worthlessness, and tiredness can all take a hefty toll on your love life. But you don't have to let depression be the demise of your relationship.