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While plenty of entertaining books have been written about the history of alcohol and other intoxicants, none have offered a comprehensive, convincing answer to the basic question of why humans want to get high in the first place. Drunk elegantly cuts through the tangle of urban legends and anecdotal impressions that surround our notions of intoxication to provide the first rigorous, scientifically grounded explanation for our love of alcohol.

It seemed like a good idea at the time. Look up Landon Roderick, that boy from childhood whom I'd never been able to forget - even though he so easily forgot about me - and call him. Then again, anything sounds like a good idea when you've had a little too much wine before bed, right? It was supposed to be just a quick, meaningless prank call. Instead I went off on him - unloading 13 years of pent-up emotions. I didn't think he'd call me back.

For Stefanie Wilder-Taylor, alcohol was the seasoning that could give almost any activity more flavor—from liquor cabinet concoctions in high school to tequila shots in her early stand-up comedy days to grocery store wine in young motherhood. A drink instantly took the edge off and made even the most difficult adversary (be it a tough crowd in a comedy club or a judgmental PTA mom) not just bearable but fun.