AI explains the critical importance of blinding and allocation concealment in randomised controlled trials (RCTs). Blinding ensures participants and researchers are unaware of treatment assignments to prevent bias in outcome assessment. Allocation concealment, implemented before treatment begins, prevents manipulation of the randomisation sequence. Different levels of blinding (single, double, triple) are described, along with the consequences of failing to maintain these crucial aspects of RCT methodology. The audio also details various methods for ensuring allocation concealment.
Dec 29 202414 Min.