• LeVar Burton: Level of Excellence
    Feb 19 2026

    LeVar Burton and Rob Lowe have no plans to retire! The legendary actor, writer, and television host returns to the show to discuss the new season of “Trivial Pursuit,” writing his much-anticipated memoir, Rob’s recent rewatch of “Roots,” why LeVar is glad he didn’t land a different game show hosting gig, and much more. Make sure to subscribe to the show on YouTube at YouTube.com/@LiterallyWithRobLowe! Got a question for Rob? Call our voicemail at 323-570-4551. Your question could get featured on the show!


    Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.

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    47 Min.
  • Dermot Mulroney: Kombucha Trouble (Re-Release)
    Feb 16 2026

    This week, we're looking back at Rob's conversation with the great (and very handsome!) Dermot Mulroney. In this episode you’ll hear them talk about Young Guns, their shared love of regional theater, how Dermot cleared up his identity confusion with Dylan McDermott, Dermot’s second career as a recording cellist, and their jealousy of Timothée Chalamet. This episode originally aired in April 2023. Make sure to subscribe to the show on YouTube at YouTube.com/@LiterallyWithRobLowe! Got a question for Rob? Call our voicemail at 323-570-4551. Your question could get featured on the show!


    Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.

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    51 Min.
  • Rich Eisen: Never Skip the Intro
    Feb 12 2026

    Sports personality Rich Eisen, host of the "Rich Eisen Show" on ESPN and Disney+, joins Rob Lowe to discuss how gambling has changed sports, their favorite TV show theme songs, “Sinners” with Michael B. Jordan, Rob's legendary NFL hat, the Bill Belichick Hall of Fame snub, and much more. Recorded just before Super Bowl LX.

    Make sure to subscribe to the show on YouTube at YouTube.com/@LiterallyWithRobLowe! Got a question for Rob? Call our voicemail at 323-570-4551. Your question could get featured on the show!


    Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.

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    59 Min.
  • Chris Pratt: Have Mercy!
    Feb 5 2026

    Chris Pratt returns to the podcast! Rob’s good friend, golf partner, and “Parks & Rec” co-star Chris Pratt joins the show to discuss his quotable kids, his new movie “Mercy” (featuring a cameo from Chris Pratt’s actual brother), Christmas with Grandpa Arnold Schwarzenegger, Rob’s alien dinner, and much more.

    Make sure to subscribe to the show on YouTube at YouTube.com/@LiterallyWithRobLowe! Got a question for Rob? Call our voicemail at 323-570-4551. Your question could get featured on the show!


    Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.

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    48 Min.
  • Catherine O'Hara: Booties & Baby Pictures (Re-Release)
    Feb 2 2026

    In honor of her passing, we are re-sharing Rob's 2020 conversation with the brilliant actress and comedian Catherine O'Hara.

    Make sure to subscribe to the show on YouTube at YouTube.com/@LiterallyWithRobLowe! Got a question for Rob? Call our voicemail at 323-570-4551. Your question could get featured on the show!


    Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.

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    1 Std. und 10 Min.
  • Kevin O’Leary: The Shark Is in the Water
    Jan 29 2026

    Mr. Wonderful himself, Shark Tank’s Kevin O’Leary, joins Rob Lowe to discuss his acting debut alongside Gwyneth Paltrow and Timothée Chalamet in “Marty Supreme,” seventeen years of “Shark Tank,” how to build a watch collection, the future of artificial intelligence, and much more.

    Make sure to subscribe to the show on YouTube at YouTube.com/@LiterallyWithRobLowe! Got a question for Rob? Call our voicemail at 323-570-4551. Your question could get featured on the show!


    Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.

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    1 Std. und 20 Min.
  • Kevin Jonas: Music That Feels Good
    Jan 22 2026

    Kevin and Rob love to talk music, dogs, and fatherhood. Kevin Jonas joins Rob Lowe to discuss his new single, “Changing,” memories of the Jonas Brothers performing at the White House, shooting Christmas movies, their shared love for the song “Torn” by Natalie Imbruglia, and more. Plus, Kevin has questions about “9-1-1: Lone Star” and “Parks & Rec.”

    Make sure to subscribe to the show on YouTube at YouTube.com/@LiterallyWithRobLowe! Got a question for Rob? Call our voicemail at 323-570-4551. Your question could get featured on the show!


    Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.

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    55 Min.
  • Julianna Margulies: That's Life in an ER (Re-Release)
    Jan 19 2026

    This week, we're looking back at Rob's conversation with "The Good Wife" star Julianna Margulies! The two discuss meditating as a family, why she left ER, and Fraterdays! Got a question for Rob? Call our voicemail at (323) 570-4551. Yours could get featured on the show!

    Make sure to subscribe to the show on YouTube at YouTube.com/@LiterallyWithRobLowe! Got a question for Rob? Call our voicemail at 323-570-4551. Your question could get featured on the show!


    Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.

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    1 Std. und 7 Min.