GLP-1 Hub: Support, Community, and Weight Loss Titelbild

GLP-1 Hub: Support, Community, and Weight Loss

GLP-1 Hub: Support, Community, and Weight Loss

Von: Ana Reisdorf MS RD
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Join Ana Reisdorf, dietitian and GLP-1 user, where science meets support, and your weight loss journey is backed by a community that gets it. Whether you're new to GLP-1 medications like Zepbound, Wegovy, Mounjaro or Ozempic, or just looking to optimize your results, this podcast is your trusted space for expert insights, real success stories, and practical strategies to help you feel your best.

© 2026 GLP-1 Hub: Support, Community, and Weight Loss Alternative & Komplementäre Medizin Hygiene & gesundes Leben
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  • What Your GLP-1 Is Doing for Your Heart Beyond Weight Loss w/ Dr. Sirisha Vadali

    What Your GLP-1 Is Doing for Your Heart Beyond Weight Loss w/ Dr. Sirisha Vadali
    Oct 12 2026
    Send us Fan MailMost people think of a GLP-1 as a weight loss medication, but for your heart, the story starts before the scale moves much at all. Board-certified cardiologist and lipidologist Dr. Sirisha Vadali explains what the research shows about GLP-1s and cardiovascular risk, the simple routine she starts her patients on, and what she monitors along the way. You'll also hear why she doesn't recommend a GLP-1 for family history alone, and about one genetic cholesterol marker that diet and exercise can't change, a lab she says everyone should have checked once in their lifetime.**IN THIS EPISODE**- How GLP-1s went from diabetes drugs to heart protection, with or without diabetes- Why some heart benefit appears before major weight loss, and why no one knows exactly how yet- Who GLP-1s are currently indicated for in cardiovascular risk reduction, and why semaglutide (Wegovy) is the one with outcomes data so far- Why muscle mass, protein, and strength training belong in every GLP-1 plan- Dr. Vadali's simple phase one: 100 grams of protein (30 to 40 grams in the morning), 25 grams of fiber, water, and strength training twice a week at home- Watching blood pressure, heart rate, hydration, and kidney function on a GLP-1- Fatigue and low motivation after the shot: what to rule out first- Whether family history alone is a reason to start a GLP-1- The heart labs she checks, including Lp(a), ApoB, hs-CRP, and a coronary calcium score- What Lp(a) is, why it's a one-time lifetime screening, and the treatments expected in the next few years- A word of caution on buying unapproved triple agonists online- Simple longevity habits: sleep, stress, walking after meals, and the 80/20 approach- Why hunger coming back isn't a reason to panic**ABOUT THE GUEST**Dr. Sirisha Vadali, MD, is a board-certified cardiologist and advanced lipidologist specializing in prevention, cardiometabolic medicine, and women's heart health. She is program director for HonorHealth's Cardiometabolic Program in Scottsdale, Arizona, and a member of the HonorHealth Women's Heart Health team. Dr. Vadali focuses on prevention-forward care, using advanced lipid testing, coronary calcium scoring, and lifestyle medicine to help patients lower cardiovascular risk and build sustainable, healthy habits.**CONNECT WITH DR. SIRISHA VADALI**Website: https://www.sirishavadali.comInstagram: https://www.instagram.com/vadalimd/HonorHealth Cardiometabolic Program: https://www.honorhealth.com/physicians/sirisha-vadali**SPONSORS**This episode is brought to you by Timeline. When you buy a one-month supply of Mitopure Gummies, you'll get a free Discovery Size Mitopure Firming Serum, an $85 value. Go to https://www.timeline.com/glp1bundle to claim yours.This episode is also brought to you by Tyde Wellness, the GLP-1 provider Ana uses, with nutrition guidance built for GLP-1s, independent licensed providers, and a care team that answers when something comes up. Go to https://tydewellness.com/GLP1Hub and use code GLP1Hub50 for $50 off your first month.**CHAPTERS**00:00 Preview: why wait for a heart attack?00:12 What's in this episode01:07 Welcome, Dr. Sirisha Vadali02:11 How GLP-1s went from diabetes drugs to heart protection03:35 How GLP-1s protect the heart, even before weight loss05:35 Semaglutide vs. tirzepatide: which she uses and why06:17 What lower obesity rates could mean for heart health08:44 Lower BMI and high risk: lifestyle first, then a low dose10:26 Her simple phase one routine and at-home strength training13:23 Kidneys, hydration, and how often to check blood pressure14:33 Fatigue and low motivation after the shot15:59 Sponsor: Timeline16:53 Is family history a reason to start a GLP-1?18:31 The heart lab panel she recommends20:10 New Lp(a) treatments on the way21:08 What Lp(a) is and why it matters23:25 A caution on unapproved triple agonists26:41 Sponsor: Tyde Wellness27:42 Longevity basics: sleep, stress, walks, and 80/2030:29 Quick fixes, food noise, and when hunger comes back32:09 Where to find Dr. VadaliMORE FROM GLP-1 HUB📬 Get The Steady State, Ana's weekly newsletter with GLP-1 guidance from a dietitian who's on one: http://join.glp-1hub.com🎙 Subscribe wherever you listen to podcasts, and if this episode helped, leave a quick review on Apple Podcasts or Spotify - it's the single best way to help more people find the show.🌐 Shop GLP-1 essentials, meal plans, and recipes: https://shop.glp-1hub.com📷 Follow on Instagram: @glp1hub📺 Watch on YouTube: https://www.youtube.com/@GLP-1hub*Some of the links shared are affiliate links. When you make a purchase, I will receive a small commission at no cost to you. Thank you for supporting the show.*The content of this show is for informational purposes only and does not constitute medical advice. The goal of this show is to provide various points of view about GLP-1 Medications. The personal and professional opinion of the guests and their content does not necessarily reflect the opinion of Ana ...
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    33 Min.
  • Oral GLP-1 Pill for Weight Maintenance: A Dietitian's Real Results w/ Whitney Black, MS RD

    Oral GLP-1 Pill for Weight Maintenance: A Dietitian's Real Results w/ Whitney Black, MS RD
    Oct 8 2026
    Send us Fan MailA daily GLP-1 pill sounds like an easy way to maintain your weight loss, but what happens when it doesn't work like the shot did? Registered dietitian Whitney Black, who lives with type 1 diabetes, shares what happened when she switched from Zepbound to Foundayo (orforglipron) for maintenance, and why she went back after two months. You'll hear how her fullness cues, blood sugar, and insulin needs changed, and what she tells clients about weight regain. The surprise wasn't the food noise. It was a different signal that quietly went missing. This is one person's experience, not a verdict on how the pill will work for everyone.IN THIS EPISODE- Whitney's path to Zepbound with type 1 diabetes, Hashimoto's, and PCOS- Why hunger and fullness dysregulation is biology, not a personal failing- Where GLP-1s stand for type 1 diabetes, and why insulin changes need your care team- What Foundayo is (an oral GLP-1 from Eli Lilly, not tirzepatide) and how its dosing differs- How her fullness cues and blood sugar changed on Foundayo, and the roughly 15 pounds she regained in two months- Cost versus effectiveness when choosing a maintenance option- Switching back to Zepbound and slowly titrating up again- Practical and mental strategies when weight comes back after a break in medicationABOUT THE GUESTWhitney Black, MBA, MS, RD, LD, LMNT, is a registered dietitian specializing in weight management and practical nutrition for individuals using GLP-1 medications. Through her private practice and online education, she helps people navigate nutrition, weight management, and metabolic health with an evidence-based, realistic approach. Whitney also brings her own lived experience with weight management and GLP-1 medications to her work, allowing her to connect clinical expertise with the real-life experience of navigating these treatments. She is also the author of an upcoming GLP-1-focused cookbook with Fair Winds Press.CONNECT WITH WHITNEY BLACKInstagram: https://www.instagram.com/whitney.the.dietitian/Work with Whitney (Nourish): https://signup.nourish.com/providers/whitney-blackSPONSORSThis episode is brought to you by Timeline. When you buy a one-month supply of Mitopure Gummies, you'll get a free Discovery Size Mitopure Firming Serum, an $85 value. Go to https://www.timeline.com/glp1bundle to claim yours.This episode is also brought to you by Tyde Wellness, the GLP-1 provider Ana uses, with nutrition guidance built for GLP-1s, independent licensed providers, and a care team that answers when something comes up. Go to https://tydewellness.com/GLP1Hub and use code GLP1Hub50 for $50 off your first month.CHAPTERS00:00 Preview: why the pill appealed to her00:21 Introduction01:04 Welcome, Whitney Black02:17 Life before GLP-1s with type 1 diabetes, Hashimoto's, and PCOS04:54 Starting Zepbound as a dietitian06:53 Fullness cues: it's biology, not willpower08:38 GLP-1s and type 1 diabetes today12:29 Maintenance, dosing, and why she tried Foundayo12:57 What Foundayo is (and isn't)14:29 Sponsor: Timeline15:23 Foundayo dosing and the first weeks16:44 Losing the fullness signal18:53 Rising blood sugar and insulin resistance19:26 Cost versus effectiveness21:40 Back on Zepbound24:00 Advice when weight comes back after a break26:14 Sponsor: Tyde Wellness27:14 Why it's not just an appetite suppressant30:08 Where to find Whitney31:26 ClosingMORE FROM GLP-1 HUB📬 Get The Steady State, Ana's weekly newsletter with GLP-1 guidance from a dietitian who's on one: http://join.glp-1hub.com🎙 Subscribe wherever you listen to podcasts, and if this episode helped, leave a quick review on Apple Podcasts or Spotify - it's the single best way to help more people find the show.🌐 Shop GLP-1 essentials, meal plans, and recipes: https://shop.glp-1hub.com📷 Follow on Instagram: @glp1hub📺 Watch on YouTube: https://www.youtube.com/@GLP-1hub*Some of the links shared are affiliate links. When you make a purchase, I will receive a small commission at no cost to you. Thank you for supporting the show.*The content of this show is for informational purposes only and does not constitute medical advice. The goal of this show is to provide various points of view about GLP-1 Medications. The personal and professional opinion of the guests and their content does not necessarily reflect the opinion of Ana Reisdorf or GLP-1 Hub.
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    32 Min.
  • GLP-1s and Vision Loss - How Worried Should You Be? w/ Dr. Luke Sorrell

    GLP-1s and Vision Loss - How Worried Should You Be? w/ Dr. Luke Sorrell
    Oct 5 2026

    Send us Fan Mail

    If you're taking a GLP-1, headlines about sudden vision loss can leave you wondering whether the medication helping you lose weight is putting your eyesight at risk. Ana Reisdorf talks with Dr. Luke Sorrell about NAION, a rare optic nerve condition, and the semaglutide research behind those headlines. You'll learn how to put "double the risk" into perspective, what questions to bring to your doctor, and why your health history matters to the conversation.

    **IN THIS EPISODE**

    - What NAION is and how it can affect vision
    - What semaglutide studies suggest, and the limits of observational research
    - Why relative risk and absolute risk tell different parts of the story
    - How diabetes, sleep apnea, cardiovascular health, and optic nerve anatomy fit into the discussion
    - Blood pressure changes, dehydration, and rapid blood sugar changes as possible contributing factors
    - Questions to ask your prescriber and eye care professional about your individual risk
    - What remains uncertain about tirzepatide and other GLP-1 medications
    - Weighing potential eye risks alongside the benefits of GLP-1 treatment

    **ABOUT THE GUEST**

    Dr. Luke Sorrell is a board-certified internal medicine physician, Fellow of the American College of Physicians, and founder of Sorrell MD, a concierge longevity and precision telemedicine practice based in Dallas-Fort Worth, Texas, serving patients across the U.S. He trained at UT Houston McGovern Medical School and completed his residency at Baylor University Medical Center in Dallas. His career has spanned hospital medicine, primary care, and longevity medicine. Today, he works with high-performing and health-conscious individuals across the country, using tools like cardiac CT angiography, VO2 max and metabolic testing, DEXA, genomics, and advanced hormone and lipid panels to identify health risks earlier. He also advises health tech companies building the next generation of care.

    **CONNECT WITH DR. LUKE SORRELL**

    Website: https://www.sorrell-md.com
    LinkedIn: https://www.linkedin.com/in/luke-sorrell-md/
    Instagram: https://www.instagram.com/sorrellmd/
    Facebook: https://www.facebook.com/SorrellMD
    Substack: https://substack.com/@sorrellmd

    **SPONSOR**

    Tyde Wellness offers GLP-1 care with licensed providers, nutrition guidance, and ongoing support. Use code GLP1Hub50 for $50 off your first month.
    https://tydewellness.com/GLP1Hub

    **CHAPTERS**

    00:00 GLP-1s and NAION: The "double risk" headline
    01:42 Meet Dr. Luke Sorrell
    02:52 What is NAION?
    05:10 How rare is NAION?
    06:13 Diabetes, sleep apnea, and other risk factors
    07:50 What the studies show and their limitations
    10:49 Relative risk versus absolute risk
    11:58 Sponsor: Tyde Wellness
    13:22 Semaglutide, tirzepatide, and unanswered questions
    14:22 Possible mechanisms: Blood pressure, oxygen, and hydration
    19:05 Eye exams, optic nerve anatomy, and rapid A1C changes
    22:15 Questions to bring to your doctor
    24:54 Ana's Plateau Breakthrough Playbook
    26:15 Staying grounded when health headlines spread
    27:20 Retatrutide and the future of GLP-1 treatment
    29:31 Connect with Dr. Sorrell
    30:01 Weighing eye concerns against cardiovascular benefits
    31:25 Closing thoughts and podcast reviews

    MORE FROM GLP-1 HUB

    📬 Get The Steady State, Ana's weekly newsletter with GLP-1 guidance from a dietitian who's on one: http://join.glp-1hub.com

    🎙 Subscribe wherever you listen to podcasts, and if this episode helped, leave a quick review on Apple Podcasts or Spotify - it's the single best way to help more people find the show.

    🌐 Shop GLP-1 essentials, meal plans, and recipes: https://shop.glp-1hub.com
    📷 Follow on Instagram: @glp1hub
    📺 Watch on YouTube: https://www.youtube.com/@GLP-1hub

    *Some of the links shared are affiliate links. When you make a purchase, I will receive a small commission at no cost to you. Thank you for supporting the show.

    *The content of this show is for informational purposes only and does not constitute medical advice. The goal of this show is to provide various points of view about GLP-1 Medications. The personal and professional opinion of the guests and their content does not necessarily reflect the opinion of Ana Reisdorf or GLP-1 Hub.
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    32 Min.
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