Conventional wisdom about running is passed down like folklore (and sometimes contradicts itself): The right kind of shoe prevents injury - or running barefoot, like our prehistoric ancestors, is best; eat a high-fat diet - and also carbo load before a race; running cures depression - but it might be addictive; running can save your life - although it can also destroy your knee cartilage. Often it's hard to know what to believe. In Running Smart, Mariska van Sprundel, a science journalist and recreational runner who has had her fair share of injuries, sets out to explore the science behind such claims.

In her quest, van Sprundel reviews the latest developments in sports science, consults with a variety of experts, and visits a sports lab to have her running technique analyzed. She learns, among other things, that according to evolutionary biology, humans are perfectly adapted to running long distances (even if our hunter-gatherer forebears suffered plenty of injuries); that running sets off a shockwave that spreads from foot to head, which may or may not be absorbed by cushioned shoes; and that a good sports bra controls the ping pong-like movements of a female runner's breasts. She explains how the body burns fuel, the best foods to eat before and after running, and what might cause "runner's high".