Xenophobia is set in Malawi, Africa, with US soldiers acting as peacekeepers to stop a civil war erupting. When an alien spacecraft arrives in orbit, America is thrown into turmoil and US troops are withdrawn from hotspots around the globe to provide support at home. Malawi descends into chaos. Xenophobia follows a band of US Rangers that stay behind to get doctors and patients from an outlying field hospital to safety. When hundreds of alien spacecraft begin flying overhead, the dynamics of war take on an entirely new dimension.