It’s 1980s New York. Heady, excessive times. Alice Burns - a young book editor - is deep into a manuscript about the morass of family life. The observations resonate, perhaps because she has just watched her own family implode. As she reads she wonders: when did the sadness start? And could it be that unhappiness is a choice? Thus begins a great American epic which follows Alice as she navigates high school bullying, first love and sexism at an elite college, a spell in 1970s Ireland, and a tragedy that sends her stateside as the US embraces a cowboy actor named Reagan.

1984. Cléo, treize ans, qui vit avec ses parents une existence modeste en banlieue parisienne, se voit un jour proposer d'obtenir une bourse, délivrée par une mystérieuse Fondation, pour réaliser son rêve : devenir danseuse de modern jazz. Mais c'est un piège, sexuel, monnayable, qui se referme sur elle et dans lequel elle va entraîner d'autres collégiennes.

Micah Mortimer isn’t the most polished person you’ll ever meet. His numerous sisters and in-laws regard him oddly but very fondly, but he has his ways and means of navigating the world. He measures out his days running errands for work – his TECH HERMIT sign cheerily displayed on the roof of his car - maintaining an impeccable cleaning regime and going for runs (7:15 every morning). He is content with the steady balance of his life. But then the order of things starts to tilt.

At the end of the Second World War, Cyril Conroy combines luck and a single canny investment to begin an enormous real estate empire, propelling his family from poverty to enormous wealth. His first order of business is to buy the Dutch House, a lavish estate in the suburbs outside of Philadelphia. Meant as a surprise for his wife, the house sets in motion the undoing of everyone he loves. The story is told by Cyril’s son Danny, as he and his older sister, the brilliantly acerbic and self-assured Maeve, are exiled from the house where they grew up by their stepmother.

When the eight-year-old daughter of an Oxford College Master vanishes in the middle of the night, police turn to the Scottish nanny, Dee, for answers. As Dee looks back over her time in the Master's Lodging - an eerie and ancient house - a picture of a high achieving but dysfunctional family emerges: Nick, the fiercely intelligent and powerful father; his beautiful Danish wife Mariah, pregnant with their child; and the lost little girl, Felicity, almost mute, seeing ghosts, grieving her dead mother.