Welcome to Yuck Kingdom - again! Falisha Whiskers has flushed her little brother Jesse down the toilet even after she promised, no matter how annoying he is, to never ever do it again! Now she has to flush herself down onto the muddy streets made of smelly jelly fellies, even though she'd hoped to never step foot inside that gross place again.
This time Falisha discovers she is on a special mission to rescue Jessie and all the Urpie Burpies from The Toilet Paper King - the most evil king in all of Yuck Kingdom - before it's too late. Will she and a team of Slumpy Bumpies find them and get home before Falisha and Jessie's daddy comes home, or will Jessie have to stay in Yuck Kingdom with The Toilet Paper King forever?