In a darkly warped near future, lucrative disease cures are brokered on Wall Street's Genetic Stock Exchange. And the hottest consumer products are artificially synthesized humans that serve as everything from domestic slaves to combatants in savage gladiatorial games. For Jack Saxton, the young heir to genetic design powerhouse Genico Inc., these Synthates are just a fact of life...until the murder of a high-profile genetic scientist leads a pair of seasoned NYPD detectives to Genico's door.

As a small band of Synthate rebels steps up its attack on the status quo, Jack encounters a pleasure-parlor girl who opens his eyes to their cause. When he dares to sympathize with the rebels, Jack is hunted down and arrested for the murder. Sentenced to die in the brutal games on Bloomberg Island, Jack will be forced to fight - for his life, for the future of all Synthates, and for a chance to uncover the mind-bending secret buried in his past.