In the latest episode of Papers Illuminated – Člankarnica, we are joined by Nika Žibrat Kalanj from the National Institute of Chemistry, who takes us into the fascinating world of plant cells, membranes, and surprisingly clever microbial proteins. We start with the basics of what a cell membrane is and why it is much more than just a passive barrier. It’s a highly selective filter that protects the cell and controls what gets in and out. Nika explains how certain toxic proteins released into the environment by plant pathogens recognize these membranes, latch onto specific lipids, and ultimately damage plant cells.

Along the way, we explore why some of these proteins are unusually flexible, allowing them to attack a wide range of plants, and how even small differences in membrane composition can have big biological consequences. The episode also offers a behind-the-scenes look at real research life, from extracting lipids directly from vegetables to navigating long periods of failed experiments before everything finally clicks. We place these discoveries into a broader context, discussing why plant research is often overlooked, how plant diseases threaten global food production, and why understanding membrane biology at the molecular level matters for the future of agriculture. An episode for anyone curious about the hidden battles at the surface of cells and why they matter far beyond the lab.

🔬 Read the paper:

https://www.science.org/doi/10.1126/sciadv.adw6401

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In the Papers Illuminated - Člankarnica podcast, together with researchers from the National Institute of Chemistry, we present interesting and accessible explanations of their latest discoveries, published in prestigious scientific journals. We invite you to follow us on social media and send us your questions, comments, and suggestions.

https://www.ki.si/o-institutu/podkast/clankarnica/

IIn the latest episode of Papers Illuminated – Člankarnica we are joined by Elvira Boršič Mlinarič, who walks us through her recently published paper on NLRP3 inflammasome activation. We talk about how immune sensors detect danger in the cell, why where proteins gather can matter as much as what they sense, and how clustering on membranes or protein scaffolds triggers inflammatory responses. Together, we unpack complex molecular immunology concepts and place them into a broader biological and biomedical context, from fundamental mechanisms to disease relevance. An episode for anyone curious about how cells recognize trouble and respond.

🔬 Read the paper: https://www.nature.com/articles/s41467-025-60277-4

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In the Papers Illuminated - Člankarnica podcast, together with researchers from the National Institute of Chemistry, we present interesting and accessible explanations of their latest discoveries, published in prestigious scientific journals. We invite you to follow us on social media and send us your questions, comments, and suggestions.

https://www.ki.si/o-institutu/podkast/clankarnica/

In this episode of Papers Illuminated – Člankarnica, we talk with Tilen Potisk, co-author of a cutting-edge paper that develops advanced particle-based models for microbubbles and nanoscale gas vesicles, two of the most important structures used in modern biomedical ultrasound.

Tilen walks us through why encapsulated microbubbles and protein-based gas vesicles matter for imaging and drug delivery, what distinguishes them, and why modeling their mechanical behavior has been so challenging until now. This conversation opens up the nanoscale world behind ultrasound contrast agents and highlights how physics-based simulations can guide the design of next-generation therapeutic carriers. If you’re interested in soft matter physics, biomedicine, modeling, or simply enjoy clear explanations of complex science, you’ll love this episode.

🔬 Read the paper: https://pubs.acs.org/doi/10.1021/acsanm.5c02783

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In the Papers Illuminated - Člankarnica podcast, together with researchers from the National Institute of Chemistry, we present interesting and accessible explanations of their latest discoveries, published in prestigious scientific journals. We invite you to follow us on social media and send us your questions, comments, and suggestions.

https://www.ki.si/o-institutu/podkast/clankarnica/