Did you know that lung cancer rates in Yorkshire are among the highest in the country? This week in The Research Room, we're joined by Professor Rachael Murray and Bec Thorley to tell us all about the YorQuit study. Funded by Yorkshire Cancer Research, this fantastic 3-arm trial aims to find the best way to support people across Yorkshire to stop smoking and improve their lung health.

Join us as we go behind the scenes of the project and discover how the study is helping Yorkshire go smoke-free, one Greggs at a time!

Find out more about YorQuit:

https://www.york.ac.uk/healthsciences/research/trials/ytutrialsandstudies/trials/yorquit/

Music by Matthew Bailey

Biologic therapies have revolutionised the treatment of autoimmune conditions, but when patients with inflammatory joint disease face surgery, clinicians and patients have a tough choice: stop these powerful medicines and risk a painful flare up of the condition or continue them and face potential infection or compromised healing.

This week in The Research Room Professor Kulveer Mankia and Trial Manager Dr Sam Brady tell us all about the PERISCOPE trial, a randomised controlled trial designed to settle this clinical catch-22.

We discover how this study aims to provide robust evidence that could change national guidelines and improve the lives of the vast number of people living with these conditions across the UK. Plus, discover what a well-known cartoon dog has to do with the future of orthopedic surgery!

Resources from this episode:

Find out more about PERISCOPE: https://www.york.ac.uk/healthsciences/research/trials/ytutrialsandstudies/trials/periscope/#tab-2

Read about the PERISCOPE trial here: https://bmjopen.bmj.com/content/14/6/e084997

Music by Matthew Bailey

This week in the Research Room, we are joined by Consultant Hand Surgeons Emma Reay and Nick Johnson to get the full story on the SCOOTT project (Surgery versus Conservative Osteoarthritis Of Thumb Trial). This ambitious three-armed study explores a critical question: is the newer joint replacement, a traditional trapeziectomy (bone removal) or enhanced non-surgical care the best way to ease the pain of thumb arthritis.

We discuss why treatment varies so widely across the UK, the "mini hip replacement" for your hand, and the importance of gathering evidence for new surgical trends. Plus, find out how the SCOOTT acronym fared in our resident rating system!

Resources from this episode:

Find out more about the SCOOTT project here: https://www.scoott-trial.com/

Thumb replacement:

Music by Matthew Bailey