Tom Lewis, DVM, DACVD is back on the podcast! Last year, Dr. Lewis joined the podcast last year to discuss the release of Zenrelia. One year later, he is back to discuss his experience with having this medication for a year and the relief it has provided for hundreds of his canine patients. Also, we discuss the recent change to the US boxed label warning which removed the vaccine induced disease portion of the label.

Learn more on this week's episode of The Derm Vet podcast!

Studies mentioned in podcast:
Recent study regarding vaccine booster response in dogs receiving Zenrelia: Fent, G.M., Jacela, J., Plazola-Ortiz, R. et al. Immunologic response to first booster vaccination in dogs treated with zenrelia™ (ilunocitinib tablets) at up to three times the recommended therapeutic dose compared to untreated controls. BMC Vet Res 21, 481 (2025). https://doi.org/10.1186/s12917-025-04929-z

Recent study regarding safety of Zenrelia: S. Forster, C. M. Trout, S. Despa, A. Boegel, D. Berger, and S. King, “ Efficacy and Field Safety of Ilunocitinib for the Control of Allergic Dermatitis in Client-Owned Dogs: A Multicenter, Double-Masked, Randomised, Placebo-Controlled Clinical Trial,” Veterinary Dermatology (2025): 1–13, https://doi.org/10.1111/vde.70009.

Timestamps
00:00 Intro
02:46 Zenrelia box label warning change
08:14 What does the box label warning change mean and why it's only in the US?
12:10 Looking at every patient as an individual
17:00 How comfortable do you feel using Zenrelia long-term?
22:14 Outro

Otitis is a common thing for veterinarians to treat. Commonly associated with underlying allergies, we can see other things cause ear infection such as ear canal masses, endocrinopathies, etc.

When you are busy in the clinic, it can be hard to think about every aspect of ear canal disease. In an attempt to make things a bit easier, I put together the top 5 mistakes I recognize in management of otitis cases. Let me preface with the fact that I have also made these mistakes in the past! Learn more on this week's episode of The Derm Vet podcast!

00:00 Intro
01:49 Mistake #1: Not performing ear cytology
05:18 Not implementing appropriate ear flushing protocol
07:46 Fail to control inflammation
09:45 Don’t recheck progress
12:14 Not identifying the underlying issue
14:49 Recap / Final Thoughts
16:27 Outro

As always, you bring the best questions for these grab bag episodes. Today, we cover dog autoimmune diseases (though cats find their way to make it in a bit).

How do you tell the difference between DLE and PF?

What if an owner can't biopsy the case?

How do you treat SLO? Sebaceous adenitis?

Find the answers to these questions and more on this week's episode of The Derm Vet podcast!

00:00 Intro
01:30 SLO & sabaceous adenitis
09:40 Steroids and Autoimmune diseases
12:23 What to do when owners can’t biopsy the case
15:12 Pemphigus foliaceus in Dogs
16:05 Pemphigus foliaceus in Cats
17:07 Autoimmune Disease vs Allergies
18:31 Differentiating between DLE and Pemphigus Exfoliation in dogs
21:48 Outro