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Sequencing by Expansion (SBX)

Sequencing by Expansion (SBX)

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After 454 now the second try by Roche: Axelios.


Preprint: https://www.biorxiv.org/content/10.1101/2025.02.19.639056v1


Read here about the PoC: https://www.pnas.org/doi/full/10.1073/pnas.1601782113


Current state (2025): https://www.nejm.org/doi/full/10.1056/NEJMc2512825


Correction: the 5B flow cell will arrive for the NovaseqX(+), not for the Nextseq2000


Also:

PacBio makes sequencing cheaper: https://www.pacb.com/press_releases/pacbio-announces-major-advances-for-revio-and-vega-to-lower-genome-cost-and-expand-multiomic-capabilities/⁠


Roche about SBX: https://sequencing.roche.com/global/en/article-listing/sequencing-platform-technologies.html


Roche from a conference: https://www.youtube.com/watch?v=YN2meswiCiQ



Since 2018, West German Genome Center (⁠https://wggc.de/⁠) operates as the next generation sequencing facility and supports research in genomics & transcriptomics by providing expertise and sequencing services. WGGC is a part of the Next Generation Sequencing Competence Network (NGS-CN: ⁠https://ngs-kn.de/⁠) – network of NGS core facilities in Germany. Listen to our podcast and we're happy to receive your feedback&questions via Email (podcast[dot]explain[at]gmail[dot]com ).

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This podcast including all episodes, unless otherwise noted, is licensed under a ⁠⁠⁠⁠⁠Creative Commons Attribution 4.0 International License⁠⁠⁠⁠⁠.You are free to share, remix, and use this content as long as you give appropriate credit, provide a link to the license, and indicate if changes were made.

Attribution:

Podcast Title: Explain Podcast

Creators: Iuliia Novoselova, Daniel Rickert

Website: ⁠⁠⁠⁠⁠https://ngs-cn.de/explain-podcast/⁠

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