Sequencing by Expansion (SBX)
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After 454 now the second try by Roche: Axelios.
Preprint: https://www.biorxiv.org/content/10.1101/2025.02.19.639056v1
Read here about the PoC: https://www.pnas.org/doi/full/10.1073/pnas.1601782113
Current state (2025): https://www.nejm.org/doi/full/10.1056/NEJMc2512825
Correction: the 5B flow cell will arrive for the NovaseqX(+), not for the Nextseq2000
Also:
PacBio makes sequencing cheaper: https://www.pacb.com/press_releases/pacbio-announces-major-advances-for-revio-and-vega-to-lower-genome-cost-and-expand-multiomic-capabilities/
Roche about SBX: https://sequencing.roche.com/global/en/article-listing/sequencing-platform-technologies.html
Roche from a conference: https://www.youtube.com/watch?v=YN2meswiCiQ
Since 2018, West German Genome Center (https://wggc.de/) operates as the next generation sequencing facility and supports research in genomics & transcriptomics by providing expertise and sequencing services. WGGC is a part of the Next Generation Sequencing Competence Network (NGS-CN: https://ngs-kn.de/) – network of NGS core facilities in Germany. Listen to our podcast and we're happy to receive your feedback&questions via Email (podcast[dot]explain[at]gmail[dot]com ).
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This podcast including all episodes, unless otherwise noted, is licensed under a Creative Commons Attribution 4.0 International License.You are free to share, remix, and use this content as long as you give appropriate credit, provide a link to the license, and indicate if changes were made.
Attribution:
Podcast Title: Explain Podcast
Creators: Iuliia Novoselova, Daniel Rickert
Website: https://ngs-cn.de/explain-podcast/
