Immune explains a study demonstrating T cells that react with SARS-CoV-2 epitopes in individuals who have never been infected with the virus, implying cross-reactivity with common cold coronaviruses.

Hosts: Vincent Racaniello and Cynthia Leifer

Guest: Brianne Barker

Subscribe (free): iTunes, Google Podcasts. RSS, email
Become a patron of Immune!

• Cross-reactive coronavirus CD4+ T cells (Science)
• Immune misfiring in severe COVID-19 (Nature)
• A COVID-19 riddle for the immune system (Nature)
• Letters read on Immune 34
• Time stamps by Jolene. Thanks!

Music by Steve Neal.
Immune logo image by Blausen Medical

Send your immunology questions and comments to immune@microbe.tv

Immune explains a study of 125 COVID-19 patients by deep immune profiling, which revealed three immunotypes associated with poor clinical prognosis or recovery.

Hosts: Vincent Racaniello and Cynthia Leifer

Guest: Brianne Barker

Subscribe (free): iTunes, Google Podcasts. RSS, email

Become a patron of Immune!

Links for this episode

• CD8 cells defend against SARS-CoV (J Virol)
• Deep immune profiling of COVID-19 patients (Science)
• Letters read on Immune 33
• Image credit
• Time stamps by Jolene. Thanks!

Music by Steve Neal.
Immune logo image by Blausen Medical

Send your immunology questions and comments to immune@microbe.tv

Immune continues a discussion of the immune response to infection with SARS-CoV-2, including inflammatory responses and disease, antibody and T-cell responses, and vaccines, and answers to listener questions.

Hosts: Vincent Racaniello, Stephanie Langel, and Cynthia Leifer

Guest: Brianne Barker

Subscribe (free): iTunes, Google Podcasts. RSS, email
Become a patron of Immune!

Links for this episode

• Keep CoV off campus (NY Times)
• Inflammatory cytokines predict COVID-19 death (medRxiv)
• Imbalanced host response drives COVID-19 (Cell)
• Convergent antibody responses in COVID-19 patients (bioRxiv)
• Cross neutralization of SARS-CoV-2 by SARS-CoV mAb (Nature)
• Human T-cell responses to SARS-CoV-2 (Cell)
• DNA vaccine protects rhesus macaques (Science)
• Replicon RNA vaccine protects macaques (bioRxiv)
• Letters read on Immune 32
• Image credit
• Time stamps by Jolene. Thanks!

Music by Steve Neal. Immune logo image by Blausen Medical

Send your immunology questions and comments to immune@microbe.tv