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How This Is Building Me

How This Is Building Me

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World-renowned oncologist D. Ross Camidge, MD, PhD, sits down with guests to discuss the highs and lows, ups and downs of all those involved with cancer, cancer medicine, and cancer science across the full spectrum of life’s experiences. Wissenschaft
  • S2 Ep2: How Physics, Medicine, and Lived Experience Shaped a Career in Breast Cancer Research and Risk Evaluation: With Ross Camidge, MD; and Sofia Diana Merajver, MD, PhD
    Feb 4 2026

    How This Is Building Me, hosted by world-renowned oncologist D. Ross Camidge, MD, PhD, is a podcast focused on the highs and lows, ups and downs of all those involved with cancer, cancer medicine, and cancer science across the full spectrum of life’s experiences.
    In this episode, Dr Camidge sat down with Sofia Diana Merajver, MD, PhD, a physician-scientist whose career bridges physics, medicine, and population health. Dr Merajver is the scientific director of the Breast Cancer Program, director of the Breast and Ovarian Cancer Risk Evaluation Program, and a professor of internal medicine and epidemiology at the University of Michigan Rogel Cancer Center in Ann Arbor. In this discussion, she reflected on a lifelong journey shaped by immigration, intellectual curiosity, and a commitment to science in service of human health. 

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    59 Min.
  • S2 Ep1: How Community Oncology Experience Built the Foundation for a Dedicated Phase 1 Research Program: With D. Ross Camidge, MD, PhD; and Justin Call, MD
    Jan 21 2026

    How This Is Building Me, hosted by world-renowned oncologist D. Ross Camidge, MD, PhD, is a podcast focused on the highs and lows, ups and downs of all those involved with cancer, cancer medicine, and cancer science across the full spectrum of life’s experiences.

    In this episode, Dr Camidge sat down with Justin Call, MD. Dr Call is a medical oncologist and hematologist at Utah Cancer Specialists in South Jordan.

    Dr Call explained that he has taken a unique professional path, transitioning from practicing as a general community oncologist to becoming a full-time phase 1 principal investigator within a community practice setting. He explained that he grew up in Salt Lake City, Utah in a family of educators and accountants, though he was heavily influenced by several uncles who were physicians, including one oncologist. After completing his medical training at the University of Colorado, he chose community oncology over academia because he wanted to remain a generalist who could treat all tumor types rather than being restricted to a specific disease group. A formative rotation at Rocky Mountain Cancer Centers solidified this desire, as Dr Call noted he was impressed by the deep knowledge required to treat various cancers and the positive atmosphere of outpatient care.

    Dr Call emphasized that his personal life significantly influenced his career choices. His son, Trevor, was diagnosed with autism at 18 months old. This diagnosis eventually led the family to move from a rural practice in Petoskey, Michigan, back to Utah to access better support services and be closer to family. His son’s experience also inspired Call's wife to earn a master’s degree in special education.

    Upon returning to Utah Cancer Specialists, Dr Call initially participated in phase 3 trials. However, he retained an interest in early-phase research from his fellowship days. In 2016, he began building a boutique phase 1 program, initially starting with just 2 hours of dedicated time per week. In 2020, his practice partnered with START (South Texas Accelerated Research Therapeutics) to launch a dedicated, full-time, community-based phase 1 program. Dr Call noted that this model is rare because phase 1 trials are highly competitive and require specialized infrastructure, such as dedicated pharmacists, coordinators, and equipment for processing pharmacokinetic samples.

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    1 Std. und 13 Min.
  • S1 Ep50: How Biostatistics Expertise Led to a Career of Propelling Ethical Clinical Trial Design: D. Ross Camidge, MD, PhD; and Tom Fleming, PhD
    Dec 24 2025
    How This Is Building Me, hosted by world-renowned oncologist D. Ross Camidge, MD, PhD, is a podcast focused on the highs and lows, ups and downs of all those involved with cancer, cancer medicine, and cancer science across the full spectrum of life’s experiences.

    In this episode, Dr Camidge sat down with Tom Fleming, PhD, a professor of biostatistics at the University of Washington School of Public Health in Seattle.

    Drs Camidge and Fleming discussed how Fleming's interest in biostatistics led to a multifaceted career in clinical trial design and analysis. Fleming pursued a PhD in math and statistics and spent his early career learning to bridge quantitative sciences with clinical medicine, working on landmark trials for adjuvant colon cancer and debunking megadoses of Vitamin C as a cancer treatment.

    A primary focus of Fleming’s career was pioneering the use of Data Monitoring Committees (DMCs) in oncology research to safeguard patient interests and trial integrity, later convincing organizations like SWOG to adopt DMCs to prevent premature data releases and biases. He also co-developed the O'Brien-Fleming monitoring boundary, a statistical framework that allows trials to stop early for efficacy only when the signal is undeniably compelling, thereby protecting scientific rigor.

    After moving to the University of Washington, Fleming expanded his focus into infectious diseases. He led international efforts that revolutionized HIV/AIDS prevention, including demonstrating a reduction in heterosexual transmission of the disease through antiretrovirals and significantly reducing mother-to-child transmission in resource-limited settings.

    Fleming remains a staunch advocate for confirmatory trials and the use of overall survival as the "gold standard" end point, often expressing skepticism toward surrogate biomarkers like progression-free survival. In the episode, he emphasized that rigorous science is possible even in the most challenging environments, provided there is a commitment to clinical equipoise and high patient retention. Outside of his professional life, Fleming prioritizes family and coaches youth soccer teams, reflecting his belief in the power of collaboration.
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    1 Std. und 11 Min.
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