Your cells depend on NAD+ to power energy production and activate repair pathways — when NAD+ declines with age, cellular function suffers.

• How NAD+ powers over 500 enzymatic reactions: Learn the specific pathways NAD+ activates — from energy metabolism (NADH in mitochondria) to DNA repair (PARP1 activation) and cellular longevity (sirtuin regulation SIRT1-7). This is not theoretical — it's foundational biochemistry that explains why NAD+ restoration matters.
• The NAMPT salvage pathway and why 85% of your NAD+ is recycled: Understand how your body maintains NAD+ efficiency through the salvage pathway, and why oral and injectable NAD+ precursors work differently than IV (which bypasses this process entirely). Sublingual and SQ delivery both activate NAMPT-mediated recycling — a key advantage for sustainable restoration.
• Clinical evidence: 59% increase at 2 weeks, 76% at 6 weeks: Real NAD+ restoration requires specific dosing and timeline expectations. Sublingual 100mg daily delivers measurable increases (verified at 2 and 6 weeks), while SQ 50–100mg weekly provides steady accumulation. This episode breaks down the timeline for what to expect and when optimization occurs.
• Three phases of NAD+ restoration: Weeks 1–3 (The Opening — initial enzymatic activation), Weeks 4–8 (Building Momentum — compounding DNA repair and metabolic shifts), Weeks 9–16+ (The Crescendo — full sirtuin regulation and sustainable energy gains). Your provider determines the delivery method (SQ or Buccal) based on your protocol — both bypass first-pass metabolism for maximum cellular access.
• Amplify NAD+ restoration with lifestyle: NAD+ precursor foods (mushrooms, dairy, poultry), high-intensity interval training (HIIT activates NAMPT), 7–9 hours of sleep (when NAD+ synthesis peaks), and stress management (cortisol suppresses NAD+ production). Your commitment drives results — this is not passive restoration.

Ready to restore your cellular energy? Schedule a consultation with Zvia Weight Loss & MedSpa to assess NAD+ candidacy and determine the right delivery method for your protocol.

Zvia Weight Loss & MedSpa | www.zvia.com | (303) 902-5353

Copyright 2026 Zvia Weight Loss & MedSpa

This content is for educational purposes only and does not constitute medical advice.

These statements have not been evaluated by the Food and Drug Administration. Treatments discussed are not intended to diagnose, treat, cure, or prevent any disease.

Individual results may vary. All protocols require provider evaluation and supervision.