In this special podcast episode, Gut Talk host Sameer Berry, MD, interviews his co-host William Chey, MD, to look back at the lessons learned throughout the milestones in his career, and discuss what lies ahead for his year as ACG president.

· Intro 1:11

· Looking back, are there Gut Talk episodes that stand out to you as being particularly memorable? 1:55

· Berry and Chey on common themes in past episodes. 4:46

· Where did you grow up and what were your childhood/early adult years like? 9:19

· Do you think your father being a division chief inspired you? 14:01

· Were there other times your father influenced you? 15:10

· Tell us more about the decisions you have made throughout your training […] Were there other influences that still guide you today? 16:58

· Are there lessons that your mentors left you with in terms of how to be a leader and think creatively? 19:50

· What about guidance you have given as a mentor? […] What advice would you give to those who want to have a leadership career within academics in today's climate? 22:10

· What does the honor of being ACG president mean to you? How did your involvement with the ACG come to be? 26:58

· What does the day-to-day look like as president of the college, and what are some of the key initiatives you are going to work on this year? 30:29

· What are some of the things that excite you most for the future of the college, the GI specialty and the health care industry? 34:26

· Thank you, Bill 37:33

· Thanks for listening 37:55

William D. Chey, MD, AGAF, FACG, is chief and professor in the division of gastroenterology and hepatology at the University of Michigan, where he leads research on diet and nutrition and their impact on functional bowel disorders. He is also co-host of Healio's Gut Talk podcast. Chey is the president of the American College of Gastroenterology (ACG) for the 2025–2026 term.

We'd love to hear from you! Send your comments/questions to guttalkpodcast@healio.com. Follow us on X @HealioGastro @sameerkberry @umfoodoc.

Disclosures: Berry and Chey report no financial disclosures.

In this podcast episode, Steven D. Leach, MD, discusses academic experiences within higher education, the influence of role models and more.

· Intro 1:11

· Steven D. Leach, MD 1:18

· Tell us about where you grew up and your family. 2:09

· Who were your early influences? 3:43

· Did you know early on that you wanted to focus on science and medicine? 5:03

· What would you say to skeptics who are critical of an Ivy League education? 5:44

· Can you tell us about speaking at the Emory School of Medicine commencement? 10:44

· How hard was it to select the story you told during the commencement speech about your patient with severe necrotizing pancreatitis? 11:56

· Tell us about your time at Yale. 15:38

· What eventually drove you from surgery to a career in basic science? 19:38

· What would you say to young people who are contemplating a career in science and academic medicine? 22:48

· What are the cultural similarities and differences in the many academic institutions you have been at? 25:52

· Was it a conscious choice to go down a more academic career pathway? […] What got you interested in developmental biology and pancreatic cancer research? 31:40

· In each of your leadership roles, how has your thinking and perspective evolved? 35:42

· Thank you, Steven 37:23

· Thanks for listening 37:32

Steven D. Leach, MD, is professor of molecular and systems biology, surgery and medicine and interim dean at Dartmouth's Geisel School of Medicine

We'd love to hear from you! Send your comments/questions to guttalkpodcast@healio.com. Follow us on X @HealioGastro @sameerkberry @umfoodoc.

Disclosures: Berry, Chey and Leach report no financial disclosures.

In this podcast episode, Paul Limburg, MD, MPH, discusses the movement from academics to industry, developments in colorectal cancer screening tools and more.

• Intro 1:11
• Paul Limburg, MD, MPH 1:17
• How did your early influences and childhood years lead you to become interested in gastroenterology and the career you have today? 1:34
• Who were your early inspirations? 2:14
• How did you transition from a career in academics and sciences to a life on the commercial side? 3:34
• How did your role at Exact Sciences come about? 5:58
• Was it a hard decision to take a new position? 7:47
• Chey and Limburg on the joy of advancing science and innovation. 9:03
• Were there any cultural differences that shocked you about the ways work is done in your previous and current positions? 10:10
• Do you see Exact outsourcing scientific research as the company grows? 12:12
• What does a typical day look like for you at Exact? […] What are you responsible of as the leading physician? 13:28
• From a product standpoint, what is ahead on the roadmap for Exact Sciences? […] What are you most excited about regarding next-generation multi-target stool testing and its impact? 15:14
• How do you respond to gastroenterologists' skepticism and concerns surrounding stool-based screening? 21:15
• What about addressing the concerns surrounding how we can ensure patients with a positive FIT test go in for a colonoscopy? 23:22
• How much of an issue are language barriers when it comes to screening tools? 28:11
• Can you talk about how Exact Sciences are using AI and the evolution of the microbiome internally or in product development? 29:42
• Do you see a future for stool-based testing in between/in combination with colonoscopies? 32:59
• Have you noticed differences in sensitivity and specificity based on age? 34:07
• What are your thoughts on making these tools available in a direct-to-consumer offering? […] How do you make these screening tools more readily available while weighing the usage risks? 35:08
• What is the rate of patients who have a positive stool-based test getting a colonoscopy? 38:44
• If you were talking to a GI fellow deciding to make the jump to industry, what do you tell them? 41:58
• Thank you, Paul 44:55
• Thanks for listening 45:21

Paul J. Limburg, MD, MPH, is chief medical officer for screening at Exact Sciences and emeritus professor of Medicine at Mayo Clinic.

We'd love to hear from you! Send your comments/questions to guttalkpodcast@healio.com. Follow us on X @HealioGastro @sameerkberry @umfoodoc. For more from Dr. Limburg, follow @limburg_paul and @ExactSciences on X.

Disclosures: Chey and Berry report no relevant financial disclosures. Limburg reports he is an employee of Exact Sciences.