The challenge of low clinical trial availability for gynaecological cancers in countries with small populations requires a unified, international approach to research. Gynae cancer patients often have limited treatment options, highlighting a massive unmet need that single institutions or smaller nations cannot solve alone.

This episode dives into the crucial work of the European Network for Gynaecological Oncological Trial Groups (ENGOT) and its collaboration with Cancer Trials Ireland. The discussion covers how this powerful collective fosters new, innovative trial options for women across Ireland and Europe, addresses recruitment challenges, and maintains an academic vision to drive patient-focused research.

Host Lucy Murphy is joined by two extraordinary leaders: Professor Isabelle Ray-Coquard, Medical Oncologist and the current Chair of ENGOT, and Professor Karen Cadoo, Gynaecology Medical Oncologist, Researcher, and one of the chairs of the Gynae DSSG at Cancer Trials Ireland. They bring deep expertise in clinical trials, oncology research, and international cooperative group collaboration

THINGS WE SPOKE ABOUT

ENGOT's history, mission, and structure.

Collaboration key to rare cancer trials.

Academic vision versus pharma priorities.

Challenges of drug reimbursement in Ireland.

Future focus: personalized gynae medicine.

GUEST DETAILS

Professor Isabelle Ray-Coquard is a Medical Oncologist and the current Chair of the European Network for Gynaecological Oncological Trial Groups (ENGOT). She is a key opinion leader in the gynae cancer space, driven by the belief that international collaboration is the only way to bring innovative therapy to patients with gynaecological cancers. She champions the importance of maintaining an academic vision in clinical trial design and ensuring database sharing for further clinician-based research.

Professor Karen Cadoo is a Gynaecology Medical Oncologist, Researcher, and one of the chairs of the Gynae Disease Specific Subgroup (DSSG) at Cancer Trials Ireland. Having worked at Memorial Sloan Kettering Cancer Centre in New York, she has extensive experience in women's health and inherited cancer genetics. She advocates for Irish patients' access to international trials, recognizing the value of the collaborative group structure for rare cancers and securing access to cutting-edge therapies that may not be locally reimbursed.5. Best Quotes with Timestamps

QUOTES

The success of ENGOT comes from two important points. One is solidarity and friendship. - Prof. Isabelle Ray-Coquard

The second point is the transparency. Everything is revealed to everybody. There is no discussion outside of behind people, and it's also because we have this transparency that we trust in each other - Prof. Isabelle Ray-Coquard

The opportunity to collaborate with international groups is so valuable to us." - Prof. Karen Cadoo

MORE INFORMATION

Cancer Trials Ireland is a registered charity and the leading cancer research trials organisation in Ireland. It aims to provide every patient with cancer access to high-quality and potentially life-altering cancer trials and to make Ireland a highly attractive location to open cancer trials. Discover more at cancertrials.ie

KEYWORDS

#GynaeOncology #ClinicalTrialsIreland #ENGOT #CancerResearch #PersonalisedMedicine

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