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Compound Interest from Semafor Business

Compound Interest from Semafor Business

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Business is changing in subtle and seismic ways. Compound Interest from Semafor Business pairs journalists Liz Hoffman and Rohan Goswami with operators, experts, and innovators behind the world’s most consequential companies, decoding why big parts of the economy work the way they do. Sign up to get the Semafor Business briefing in your inbox. This season of Compound Interest is in partnership with Amazon Business. Amazon Business is a trusted partner that transforms business buying by combining Amazon's vast selection, competitive pricing, and fast delivery with added tools and insights to help businesses simplify purchasing, manage spend, and buy smarter.2026 Semafor, Inc Politik & Regierungen Ökonomie
  • Mark Cuban on his pharma fight, Dallas Mavs regrets, and the PE-ification of sports
    Apr 28 2026
    Mark Cuban is on a mission to rid the US health care system of the middlemen he blames for soaring costs. Liz and Rohan dive into his approach with Cost Plus Drugs, which aims to disrupt the little-known middlemen driving up prescription drug prices. He also discussed soaring valuations in sports, his own regrets around the Dallas Mavericks sale, and offers a surprising assessment of TrumpRX. This season of Compound Interest is in partnership with Amazon Business. Amazon Business is a trusted partner that transforms business buying by combining Amazon's vast selection, competitive pricing, and fast delivery with added tools and insights to help businesses simplify purchasing, manage spend, and buy smarter. Photo Credit: Mark J. Rebilas-Imagn Images
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    53 Min.
  • Cloning woolly mammoths is cool. Can it be profitable?
    Apr 21 2026
    Colossal, the biotech startup working on de-extincting the woolly mammoth and the dodo, thinks it can make trillions of dollars — almost none of it from consumer-facing products. Liz and Rohan dive into it all with CEO Ben Lamm, who has already spun out four businesses as he’s built the bioscience business with a focus on serving governments and nations looking to build drought-resistant plants, plastic-munching microbes, and much more (some of it classified!) This season of Compound Interest is in partnership with Amazon Business. Amazon Business is a trusted partner that transforms business buying by combining Amazon's vast selection, competitive pricing, and fast delivery with added tools and insights to help businesses simplify purchasing, manage spend, and buy smarter.
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    40 Min.
  • America’s best energy trader on fixing higher ed and the dangers of prediction markets
    Apr 14 2026
    John Arnold — one of the greatest energy traders of his generation — turned his sights on philanthropy nearly two decades ago, applying the same ROI-driven focus that made him billions to charitable giving. He walks Liz and Rohan through his vision for fixing higher ed, the problem with sports betting and prediction markets, and the Trump-driven chaos in the energy markets. This season of Compound Interest is in partnership with Amazon Business. Amazon Business is a trusted partner that transforms business buying by combining Amazon's vast selection, competitive pricing, and fast delivery with added tools and insights to help businesses simplify purchasing, manage spend, and buy smarter.
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    43 Min.
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