When every minute counts, inefficiencies in communication and data flow can cost lives. In this episode of Biomedical Frontiers, trauma surgeon Dr. Jamie Wisser and entrepreneur Robert Holton share how they’re using AI and interoperability to accelerate time to critical care.

Dr. Wisser, founder of Actual Healthcare Solutions, describes how his experience performing 26-hour reconstructive surgeries exposed the limits of today’s electronic medical records. Together with Holton, he’s building a platform that connects hospital systems, specialists, and radiologists in real time—using AI to automate referrals, interpret imaging in seconds, and bridge the silos that slow patient care.

💡 What you’ll learn:

✅ Why healthcare still runs on disconnected “data islands”

✅ How AI-driven radiology can deliver results in under 30 seconds

✅ How interoperability can improve patient outcomes and physician efficiency

✅ Lessons from a trauma surgeon turned health tech founder

📚 Resources:

• Actual HealthCare Solutions: https://www.actualhealthcaresolutions.com
• HIT Lab: https://www.hitlab.org
• New York Innovation Week: https://www.nyinnovationweek.com

Follow Biomedical Frontiers for more:

📸 Instagram: @biomedicalfrontiers

🔗 LinkedIn: https://www.linkedin.com/company/uvacoulter

📧 Reach us: biomedicalfrontiers@virginia.edu

Love this podcast? Write to us with feedback or guest recommendations!

Production Team:

Director & Host: Dasha Tyshlek, StratCraft, Inc. www.strat-craft.com

Executive Producer: David Chen, Managing Director & Instructor of Engineering Design

Senior Producer: Hannah Moore, Associate Director, UVA Coulter

Design Director: Carolyn Wagner, Inc. & Link: carolynwagnerinc.com

Produced on behalf of: Wallace H. Coulter Center for Translational Research at University of Virginia

Type 2 diabetes affects over 37 million Americans — but what if our standard treatment paradigm is all wrong?

In this episode, Dr. Meagan Grega shares the science and strategy behind lifestyle medicine, a fast-growing movement that uses food, sleep, movement, stress reduction, and social connection to treat and even reverse chronic disease.

Dr. Grega is the co-author of the first-ever Clinical Practice Guideline on Lifestyle Interventions for Type 2 Diabetes and a lead author of ACLM’s Expert Consensus Statement on lifestyle medicine in primary care. She co-founded the Kellyn Foundation, where she helps families across Pennsylvania access fresh food, grow gardens, change lifestyle and improve their health together.

You’ll learn:

• How fat in your muscles causes insulin resistance — and how to reverse it
• What makes behavior change stick
• Why doctors don’t prescribe lifestyle medicine — and how that’s changing
• How community-based programs and school gardens are transforming lives
• New Clinical Guidelines and Expert Consensus on treating diabetes with lifestyle interventions

📚 Resources:

• Free CME course: https://lifestylemedicine.org/education-certification/course-catalog/
• Kellyn Foundation: https://www.kellyn.org/
• Dr. Grega’s TED Talk: https://www.youtube.com/watch?v=efGa8QD8pU4
• ACLM Clinical Practice Guideline: https://journals.sagepub.com/toc/ajla/19/2_suppl
• ACLM Expert Consensus Statement: Lifestyle Medicine for Optimal Outcomes in Primary Care: https://journals.sagepub.com/doi/full/10.1177/15598276231202970

Follow Biomedical Frontiers for more:

📸 Instagram: @biomedicalfrontiers

🔗LinkedIn: https://www.linkedin.com/company/uvacoulter

📧 Reach us: biomedicalfrontiers@virginia.edu

Love this podcast? Write to us with feedback or guest recommendations!

Production Team:

Director & Host: Dasha Tyshlek, StratCraft www.strat-craft.com

Executive Producer: David Chen, Managing Director & Instructor of Engineering Design

Senior Producer: Hannah Moore, Associate Director, UVA Coulter Design Director

Produced on behalf of: Wallace H. Coulter Center for Translational Research at University of Virginia

Dr. Stanley Crooke pioneered a new class of medicine—antisense oligonucleotides—and built a $5B biotech company, Ionis Pharmaceuticals, to prove it could work. Then he walked away to found a nonprofit, n-Lorem, to treat patients with one-in-a-billion genetic mutations—people no one else would help. In this episode, we explore:

• What nano-rare diseases are, and why they represent medicine’s next great frontier.
• The promise of antisense therapy for individualized, mutation-specific treatment.
• The 30-year scientific journey behind genetic medicine—and what it takes to lead through failure.
• Why n-Lorem offers a new nonprofit model for treating diseases too rare to commercialize.
• The privilege, heartbreak, and hope of doing science not just for success, but for purpose.

Mentioned Resources:

• Antisense Technology: A Review (PubMed)
• n-Lorem Foundation
• Hope Lies in Dreams – Nature’s 10-part series on Dr. Crooke
• The National Economic Burden of Rare Disease Study (EveryLife Foundation)

Follow Biomedical Frontiers for more: 📸 Instagram: @biomedicalfrontiers 🔗 LinkedIn: https://www.linkedin.com/company/uvacoulter 📧 Reach us: biomedicalfrontiers@virginia.edu Love this podcast? Write to us with feedback or guest recommendations!

Production Team: Director & Host: Dasha Tyshlek, StratCraft, Inc. www.strat-craft.com Executive Producer: David Chen, Managing Director & Instructor of Engineering Design Senior Producer: Hannah Moore, Associate Director, UVA Coulter Design Director: Carolyn Wagner, Inc. & Link: carolynwagnerinc.com Produced on behalf of: Wallace H. Coulter Center for Translational Research at University of Virginia