Being told your labs are “normal” and your cycle is still regular does not mean your metabolism and hormones are stable. Early insulin resistance can quietly increase inflammation, drive midsection fat gain, and accelerate skin aging years before menopause is officially diagnosed.

In this Biohacking Beauty episode with Dr. Jila Senemar, we break down why regular periods do not rule out perimenopause, why building muscle is one of the most powerful metabolic tools in midlife, and how early testing like DEXA scans can reveal hidden bone loss long before standard guidelines would ever check.

Dr. Jila Senemar is a board-certified OB/GYN with more than 20 years of clinical experience. She is a menopause specialist certified by The Menopause Society and a longevity physician. Her clinical work focuses on perimenopause, menopause, hormone therapy, and midlife women’s health.

What's Discussed:

• (02:57) Insulin resistance as an early midlife driver of inflammation and weight gain
• (03:35) Why more cardio and restriction can worsen midlife metabolic dysfunction
• (07:27) Regular periods and no hot flashes still align with early perimenopause
• (09:44) Night waking and unrefreshing sleep as overlooked perimenopause symptoms
• (15:01) Strength training as a metabolic and hormonal support tool in midlife
• (24:40) Using DEXA scans at 40 to detect early bone density loss
• (26:15) Hormone therapy framed around longevity, not just symptom relief
• (41:14) Progesterone’s role in sleep, mood stability, and early perimenopause support

Find more from Young Goose:

• The Elastin Action Protocol → Engineered for Skin Navigating Elasticity Change
• The Winter Skin Protocol → Build for How Skin Actually Behaves in Winter
• VAMPIRE EXOSOMES → Professional Exosome Serum for Regeneration and Post-Treatment Recovery
• Use code PODCAST10 to get 10% off your first purchase, and if you’re a returning customer use the code PODCAST5 to get 5% off at https://younggoose.com
• Instagram: @young_goose_skincare

Find more from Dr. Jila Senemar MD, FACOG, MSCP:

• Website: https://www.jilamd.com
• Instagram: @drjilasenemar

Advanced skincare routines are more popular than ever, yet dryness, laxity, and visible aging still persist. The issue isn’t effort or discipline. It’s that skin aging is being treated as a surface-level problem instead of a cellular and structural one.

We dive deeper into this in the latest Biohacking Beauty Podcast with Jess Kane. We also chat about how cell membrane health shapes visible aging, why omega fats are widely misunderstood, and how most “liposomal” supplements never reach the cell.

Jessica Kane is the Co-Owner and Chief Marketing Officer of BodyBio, a third-generation wellness company specializing in cellular health. She works alongside healthcare practitioners and researchers to translate complex cell membrane and lipid science into practical, evidence-based solutions.

What's Discussed:

• (06:17) Why advanced skincare and red light therapy still fail without cellular building blocks
• (07:37) How low-fat nutrition and missing lipids weaken skin structure over time
• (09:55) Cell membranes explained as the foundation of skin barrier, tone, and elasticity
• (10:46) How phospholipids act as the “cement” between skin cells and prevent laxity
• (13:15) Why the omega-6 to omega-3 ratio matters more than taking fish oil alone
• (15:57) Why most phosphatidylcholine on the market is not truly liposomal
• (18:28) How “liposomal” labeling works and why most supplements fail cellular delivery
• (36:01) Why vitamin C and glutathione don’t impact collagen without proper absorption

Find more from Young Goose:

• Find our Elastin Protocol here: https://younggoose.com/pages/elastin-action-protocol-landing
• Find our Winter Protocol here: https://younggoose.com/pages/winter-protocol
• VAMPIRE EXOSOMES → Professional Exosome Serum for Regeneration and Post-Treatment Recovery: https://younggoose.com/products/vampire-exosomes
• Use code PODCAST10 to get 10% off your first purchase, and if you’re a returning customer use the code PODCAST5 to get 5% off at https://younggoose.com/?utm_source=podcast&utm_medium=apple
• Instagram: http://instagram.com/young_goose_skincare

Find more from Jess Kane:

• Website: https://bodybio.com/
• Instagram: https://instagram.com/jesskane
• Instagram: https://www.instagram.com/bodybio/
• Tiktok: https://tiktok.com/@jesskaneb

It’s Valentine’s Day, and while we don’t usually shape our work around holidays, this one felt different because we’re not just co-founders of Young Goose, we’re life partners. For us, care has always shown up in daily choices and consistency, the same philosophy behind how we think about skin longevity.

In this special episode, we flip the format and recommend ingredients to each other based on real-time skin needs. We get into methylene blue, NAD support, ectoin, retinol, and repair-focused actives through the lens of cellular energy, inflammation control, repair, and long-term resilience.

If you’re listening on Valentine’s Day, we’re honored you’re spending it with us. And if you’re tuning in any other day, we’re just as glad you’re here. Either way, this conversation is about care that lasts and the small, intentional choices that add up over time.

What's Discussed:

• (03:38) Why this Valentine’s episode feels different as co-founders and life partners
• (06:11) Recommending ingredients based on real-time skin needs, not bias
• (12:38) Methylene blue, red light synergy, and mitochondrial skin energy
• (17:04) NAD support as the currency behind repair and long-term resilience
• (20:49) Ectoin, deep hydration, and protection from blue light and pollution
• (25:10) Retinol results, limitations, and why peptide alternatives matter
• (27:36) Sun exposure, oxidative stress, and the missing piece of post-UV DNA repair

Find more from Young Goose:

• The Elastin Action Protocol → Engineered for Skin Navigating Elasticity Change
• The Winter Skin Protocol → Build for How Skin Actually Behaves in Winter
• VAMPIRE EXOSOMES → Professional Exosome Serum for Regeneration and Post-Treatment Recovery
• Use code PODCAST10 to get 10% off your first purchase, and if you’re a returning customer use the code PODCAST5 to get 5% off at https://younggoose.com
• Instagram: @young_goose_skincare