All Access DNA Titelbild

All Access DNA

All Access DNA

Von: allaccessdna
Jetzt kostenlos hören, ohne Abo

Saisonale Sparangebote | 0,99 € pro Monat für die ersten 3 Monate

Danach 6,99 €/Monat. Bedingungen gelten. Monatlich kündbar.
Want to know more about your DNA? Curious about how your genes impact your health? All Access DNA honestly answers the questions you have about genetics, healthcare, and popular issues in genomic medicine. Host Kate Wilson utilizes her genetic expertise and experience to interview leaders and specialists in genomic health and research. Join us as we bring you understandable, scientific information about genetics!Constellation Genetics LLC, Copyright 2025 All rights reserved. Hygiene & gesundes Leben Wissenschaft
Folgen
  • MTHFR Gene: What’s real, what’s not and what does it actually mean?

    MTHFR Gene: What’s real, what’s not and what does it actually mean?
    Oct 6 2026

    In today's conversation, Kate Wilson welcomes Emalyn Cork to explore the complexities of the MTHFR gene, a topic that has sparked curiosity and confusion alike in both clinical settings and the general public. Emalyn explains the complexities of the MTHFR gene, debunks common misconceptions, and discusses when genetic testing is truly necessary.

    Key words:

    MTHFR, genetics, homocysteine, genetic testing, medical misinformation, folic acid, genetic variants, health risks, clinical utility, genetic counseling

    Key Topics:

    • What the MTHFR gene does in the body
    • Common misconceptions about MTHFR variants
    • When genetic testing for MTHFR is clinically relevant
    • Risks of unnecessary genetic testing and treatments
    • How to interpret genetic test results responsibly

    Guest bio:

    Emalyn is the Assistant Director of Genetic Counseling at Emory Healthcare. She works with pediatric and adult clinical genetics patients in the inpatient and outpatient settings. She graduated from Mount Sinai's genetic counseling training program in 2018 and worked as a genetic counselor in their clinic for inborn errors of metabolism before moving to Atlanta to join Emory's team in 2021. She has a special interest in metabolic and mitochondrial diseases and is passionate about the education and mentorship of genetics trainees.

    Resources related to today’s topic:

    • Findageneticcounselor.org to search for a genetic counselor near you
    • Information on MTHFR from Cleveland Clinic

    Give your feedback and help shape All Access DNA! Take our listener survey here: https://forms.gle/x82MKLRftpKH987s7

    Sign up for our newsletter here: https://www.allaccessdna.com/newsletter

    Please subscribe to this podcast on Apple Podcasts, Spotify, YouTube or wherever you get your podcasts to stay updated on new episodes of All Access DNA. Listen to past episodes on your favorite podcast play by searching “All Access DNA” or by streaming from our website at allaccessdna.podbean.com

    Any inquiries on the podcast can be sent to AllAccessDNA@gmail.com

    Note that this podcast is for entertainment and education and is not intended to be a substitute for professional medical advice. Please consult your physician with any questions you may have regarding your health.

    The All Access DNA team includes: host, producer and editor Kate Wilson. The logo is designed by Designs by NKJ. Our Social Media Lead is Aryanah Estinvil.
    Mehr anzeigen Weniger anzeigen
    39 Min.
  • #64- Should we select embryos based on chance?

    #64- Should we select embryos based on chance?
    Sep 22 2026

    Dr. Betty Cohn discusses the complexities, ethical considerations, and current state of polygenic embryo screening and risk scores, highlighting the scientific, ethical, and societal challenges involved.

    Key words: polygenic embryo screening, genetic testing, reproductive ethics, risk scores, embryo selection, genetic diversity, clinical validity, reproductive autonomy, bioethics

    Key Topics:

    • What polygenic embryo screening is and how it differs from single-gene testing
    • The probabilistic nature of polygenic risk scores and their limitations
    • Ethical implications of embryo selection based on risk scores
    • Disparities and biases in polygenic risk scoring across ancestry groups
    • The influence of commercial companies and lack of regulation in direct-to-consumer genetic testing
    • The impact of societal values in embryo selection

    Guest bio:

    Betty Cohn is a postdoctoral fellow working with Dr. Anna Wexler at the University of Pennsylvania. She holds a PhD in Public Health Genetics from the University of Washington, a Master of Bioethics from the Johns Hopkins Berman Institute of Bioethics, and a B.A. from Binghamton University. Her research examines the ethical, legal, and social implications of emerging biotechnologies, including direct-to-consumer genetic testing, brain organoids, and polygenic risk scores. Her doctoral dissertation used qualitative methods to explore how individuals who discover a misattributed parentage experience through genetic testing navigate these findings, with a focus on online communities as sources of social support.

    LinkedIn: https://www.linkedin.com/in/bettycohn/

    Twitter/X: @bettyccohn

    Resources related to today’s topic:

    • “Ethical and social implications of implementing polygenic embryo screening into clinical care: A scoping review” by Betty Cohn, Dorit Barlevy, Gabriel Lazaro-Munoz
    • “Polygenic risk scores in the clinic: Health-system leaders and primary care providers weigh in” by Susan Brown Trinidad, Stephanie M Fullerton, Betty Cohn, David R Crosslin, Gail P Jarvik
    • “Human Demographic History Impacts Genetic Risk Prediction across Diverse Populations” by Martin et al.

    Give your feedback and help shape All Access DNA! Take our listener survey here: https://forms.gle/x82MKLRftpKH987s7

    Sign up for our newsletter here: https://www.allaccessdna.com/newsletter

    Please subscribe to this podcast on Apple Podcasts, Spotify, YouTube or wherever you get your podcasts to stay updated on new episodes of All Access DNA. Listen to past episodes on your favorite podcast play by searching “All Access DNA” or by streaming from our website at allaccessdna.podbean.com

    Any inquiries on the podcast can be sent to AllAccessDNA@gmail.com

    Note that this podcast is for entertainment and education and is not intended to be a substitute for professional medical advice. Please consult your physician with any questions you may have regarding your health.

    The All Access DNA team includes: host, producer and editor Kate Wilson. The logo is designed by Designs by NKJ. Our Social Media Lead is Aryanah Estinvil.
    Mehr anzeigen Weniger anzeigen
    36 Min.
  • #63-How can you cure ALS & FTD in a race against time?

    #63-How can you cure ALS & FTD in a race against time?
    Sep 8 2026
    In this episode, Yentli Soto Albrecht, PhD, shares her personal journey with ALS and FTD, her scientific research, and her efforts to accelerate the search for a cure. Discover how her story fuels her advocacy and innovative projects to fight these neurodegenerative diseases. Key words: ALS, FTD, genetic research, neurodegeneration, Cure C9, gene therapy, prevention trials, scientific collaboration, patient advocacy Key Topics: Genetic causes of ALS and FTD and the C9 repeat expansionCurrent challenges in clinical trials and drug developmentThe role of patient advocacy and community engagementInnovative research projects and collaborationsThe importance of accessible biomarkers and diagnostics Guest bio: Yentli Soto Albrecht, PhD, is a 9th-year MD-PhD student at the University of Pennsylvania and will complete her medical degree in 2027. She earned her PhD in 2024 in the Douglas Wallace lab at the Children’s Hospital of Philadelphia, showing that mitochondrial oxidative phosphorylation restricts SARS-CoV-2 replication and that natural mitochondrial DNA variation modulates viral pathogenesis, work recognized with the Richard K. Root Prize for Infectious Disease Research in 2025. She was president of the American Physician Scientists Association from 2022 to 2023, managing a budget of more than $300,000 and reaching over 5,000 dual-degree applicants across her five-year tenure. She was preparing for a career as an infectious disease physician-scientist when her father was diagnosed with genetic ALS in June 2023 and she learned she carried the same C9orf72 repeat expansion that was taking his life, the most common genetic cause of both ALS and frontotemporal dementia (FTD). Her father, Frank Albrecht, died in August 2024, and six months later she pivoted to C9orf72 neurodegeneration. She has since built eleven collaborative projects across eight countries, including synchrotron imaging comparing aggregates in C9 ALS and C9 FTD, nanosensor-based biomarker discovery, drug repositioning, and the first commercial C9orf72 iPSC biorepository, which begins with her father’s cells and her own. She has secured more than $280,000 in grant funding for her collaborators and raised over $66,000 through Push Ups for ALS, a carrier-led fundraiser in her father’s memory. She co-founded CureC9, a program within EverythingALS governed by an eight-member scientific advisory board, which has raised $216,711 toward a $12 million flagship effort and meets for the third time in September to plan the first prevention trial for genetic ALS and FTD. She was the inaugural End the Legacy Community Science Liaison fellow, brings the science back to genetic carriers in lay terms through her video series Search for a Self Cure, and has accepted an offer to join Eli Lilly’s Talent Development Academy in Boston as a postdoctoral scientist in ALS disease biology and drug discovery after medical school. Next year, she will apply to neurology residency programs for a 2028 start. Dr. Soto Albrecht draws on her position as patient, scientist, and physician-in-training to accelerate therapies for familial ALS and FTD within her lifetime. Resources related to today’s topic: CureC9 websiteThe Association for Frontotemporal DegenerationThe ALS AssociationCompassionate Care ALSNorth Star ALSEnd the LegacyEverything ALSBreakthrough Prize Video Give your feedback and help shape All Access DNA! Take our listener survey here: https://forms.gle/x82MKLRftpKH987s7 Sign up for our newsletter here: https://www.allaccessdna.com/newsletter Please subscribe to this podcast on Apple Podcasts, Spotify, YouTube or wherever you get your podcasts to stay updated on new episodes of All Access DNA. Listen to past episodes on your favorite podcast play by searching “All Access DNA” or by streaming from our website at allaccessdna.podbean.com Any inquiries on the podcast can be sent to AllAccessDNA@gmail.com Note that this podcast is for entertainment and education and is not intended to be a substitute for professional medical advice. Please consult your physician with any questions you may have regarding your health. The All Access DNA team includes: host, producer and editor Kate Wilson. The logo is designed by Designs by NKJ. Our Social Media Lead is Aryanah Estinvil.
    Mehr anzeigen Weniger anzeigen
    53 Min.
adbl_web_anon_alc_button_suppression_t1
Noch keine Rezensionen vorhanden