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Active Ingredients

Active Ingredients

Von: Fraser Dove International
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 The Active Ingredients podcast dissects the very essence of exceptional leadership in the life sciences. Our quest is to educate, motivate, and inspire life science professionals to soar to new heights of visionary leadership. Join host Thomas Dove, Co-Founder at Fraser Dove International, as he delves into enriching discussions at the intersection of science and leadership. Wherever you are in your career journey, whether just starting out or leading a team or department, you'll discover a wealth of practical insights and wisdom to carve your leadership journey in the life sciences.Fraser Dove International Management & Leadership Ökonomie
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  • Strategy Meets Reality in Pharma Manufacturing Transformation with Karsten Pietron-Kattmann

    Strategy Meets Reality in Pharma Manufacturing Transformation with Karsten Pietron-Kattmann
    Feb 16 2026
    In this episode of the Active Ingredients podcast, host Thomas Dove interviews Karsten Pietron-Kattmann, Strategic Advisor at k2pharmaCon. Karsten Pietron-Kattmann has spent his career leading operational transformation at major pharmaceutical companies including Novartis, GSK, Bayer, and BioNTech, where he played a key role during the Covid vaccine response. In this conversation, he shares his framework for aligning strategy, culture, and organisation during transformation. He explains how pharmaceutical leaders can drive change by focusing on what teams can control, tailoring communication to different audiences, and building trust that survives uncertainty. From leading through the Covid vaccine response to managing site divestments during lockdown, Karsten reveals what transformation looks like when strategy meets operational reality. Key Takeaways Understand the magic triangle framework that connects strategy, culture, and organisation in pharmaceutical transformation, and why changes fail when leaders underestimate how disruption in one area affects the others. Learn why authenticity forms the foundation of effective leadership in pharmaceutical and biotech organisations, and how trying to be someone else erodes team trust and credibility. Discover how trust operates across three levels in life sciences companies: trusting your employees, trusting your own capabilities, and trusting your organisation to navigate complexity. Understand how early career experiences shape leadership approaches. Karsten Pietron-Kattmann’s path from lab technician to executive taught him empathy for frontline teams and the value of hands-on operational understanding. Explore how collaboration solves problems that individual teams cannot address alone, and why successful leaders look beyond their immediate resources to find solutions across organisations. Gain practical insight into leading global teams across different cultures and accepting that multiple pathways can reach the same goal, even when they differ from your preferred approach. Apply lessons about balancing technology adoption with human-centered leadership as artificial intelligence (AI) and data analytics reshape how life sciences organisations operate and make decisions. Snippets “Self-confidence without reflection is not such a sharp knife." "The worst you can do to teams is to take away the purpose of their work and the purpose of their day-to-day efforts. You will have a break of loyalty and integrity in your team." "If you spent most of the time making slides for the review, you will not focus on delivering on the clean room wall, on the HVAC system, on the process machinery." Timestamps & Topics The following timestamps are approximations: [21:23] – Intro: Karsten Pietron-Kattmann's leadership journey in biopharma [23:37] – Key Ingredients: Authenticity, trust, curiosity in pharma leadership [26:29] – Career Path: From lab technician to pharmaceutical executive roles [29:31] – Mentorship: Early influences shaping collaboration and problem solving [77:27] – Cultural Leadership: Managing global teams across different methodologies [79:31] – Industry Outlook: Modular manufacturing and AI in life sciences [82:07] – Future Leaders: Embracing diversity and technology in biopharma teams Resources Follow Karsten Pietron-Kattmann on LinkedIn: https://www.linkedin.com/in/karsten-pietron-kattmann-7300ba24/ Follow Thomas Dove on LinkedIn: https://www.linkedin.com/in/lifesciencesexecutivesearch/ Don't Miss an EpisodeSign up to the Active Ingredients podcast at ⁠www.activeingredients.fraserdove.com⁠.Remember to tune into our next episode for more inspiring insights. You can also subscribe to the Active Ingredients podcast on ⁠Apple Podcasts⁠, ⁠Amazon⁠, ⁠Spotify⁠, ⁠YouTube⁠ and other leading podcast platforms.Loved this episode?Share it with your friends, family, or your peers!
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    1 Std. und 5 Min.
  • Trust, Vision, and Human-Centred Leadership With Thomas Jaecklin

    Trust, Vision, and Human-Centred Leadership With Thomas Jaecklin
    Feb 2 2026
    In this episode of the Active Ingredients podcast, host Thomas Dove interviews Thomas Jaecklin, Chief Medical Officer and Strategic Pharma Consultant at TJ Pharma Consulting.Thomas shares his journey from paediatric intensive care physician to C-suite executive, revealing how clinical precision and human-focused leadership create sustainable success in biotech and pharma. The conversation explores trust building, team dynamics, leadership transitions during company maturation phases, and how globalisation is reshaping pharmaceutical leadership.Key TakeawaysLearn how generating trust serves as the foundation for effective leadership, creating environments where teams communicate early warnings and innovate freely.Discover why vision requires constant communication, as leaders must continuously refocus teams, investors, and partners toward shared goals through repetitive messaging.Understand how self-awareness drives leadership development, particularly how doubting yourself can become a strength when it helps identify your own blind spots.Explore complexity differences between hospital and pharma leadership, where drug development requires integrating diverse mindsets from commercial, regulatory, safety, and scientific teams.Take away frameworks for recognizing leadership expiry dates during transitions, especially when projects move from research to clinical development or development to commercialization.Gain insights into building teams using the bicycle wheel analogy, where elements like psychological safety and integrity must be strengthened iteratively rather than focusing on single aspects.Apply hiring strategies that prioritize belief over checkbox qualifications, understanding how playing into strengths creates more energised teams than forcing fit against rigid job descriptions.Snippets"Building high performing teams is like building a bicycle wheel… You can't go and connect the hub to the rim and tension that first spoke to the desired tension…, ignoring all the other spokes…"“I'd rather play into someone's strengths and try and fill the gaps that this person leaves open…, because that person will be much more motivated, will be much more energised, fulfilled…”“It's not the computers or the machines that we buy that make the great work. It's the people that operate those computers and machines…. So why are we treating people so badly?”Timestamps & TopicsThe following timestamps are approximations:00:20:44 - Three Key Ingredients: Trust, vision, and constant communication as leadership foundations00:28:24 -- Transition to Industry: Moving from academic medicine to pharma's collaborative research environment00:32:04 - Becoming a Leader: Recognizing impact through team feedback and psychological safety00:36:19 - Hospital vs. Pharma: Understanding complexity and diverse team mindsets00:44:19 - Leadership Expiry Dates: Navigating transitions from research to development to commercialisation00:54:12 - Building High-Performing Teams: The bicycle wheel framework for iterative trust building01:04:23 - China's Innovation Challenge: How rapid development is reshaping global PharmaResourcesFollow Thomas Jaecklin on LinkedIn: https://www.linkedin.com/in/thomas-jaecklin/Follow Thomas Dove on LinkedIn: https://www.linkedin.com/in/lifesciencesexecutivesearch/Don't Miss an EpisodeSign up to the Active Ingredients podcast at www.activeingredients.fraserdove.com.Remember to tune into our next episode for more inspiring insights. You can also subscribe to the Active Ingredients podcast on Apple Podcasts, Amazon, Spotify, YouTube and other leading podcast platforms.Loved this episode?Share it with your friends, family, or your peers!
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    54 Min.
  • Building Patient-Focused Teams with Nageatte Ibrahim

    Building Patient-Focused Teams with Nageatte Ibrahim
    Jan 19 2026
    In this episode of the Active Ingredients podcast, host Thomas Dove interviews Nageatte Ibrahim, CEO and Founder of Arc Nouvel Clinical Development Consulting LLC.Ibrahim’s journey spans board-certified medical oncologyist, leadership of oncology trials at Merck, Chief Medical Officer at Arc Nouvel Clinical Development Consulting LLC, and now clinical development consultant for early- and mid-sized biotechs. This episode explores her evolution from hands-on patient care to executive leadership, focusing on the critical balance between clinical excellence and commercial viability. Her insights on building inclusive teams, leading through uncertainty, and maintaining patient focus while scaling biotech organisations offer practical guidance for life sciences executives navigating the modern-day pharmaceutical landscape.Key Takeaways• Learn how caring for people forms the foundation of leadership, recognising that, as a leader, you’re entrusted with the careers and futures of others in pharmaceutical and biotech organisations.• Discover the power of clear focus and realistic goals to align teams behind a shared mission, preventing the chaos that emerges when people move in different directions without understanding their roles.• Understand the critical distinction between leading and bringing people along, as Ibrahim explains how great leaders avoid leaving team members behind while pursuing business objectives.• Explore how early mentorship shapes career trajectories through Ibrahim’s experience with hands-on tumor sample research as an undergraduate, demonstrating the lasting impact of invested leadership on emerging talent.• Take away strategies for growing the next generation of leadership by serving as a model for inclusive, mission-focused team building that develops future pharmal executives.• Gain insights into leading virtual teams in life sciences, including the essential practice of one-on-one conversations to read what body language and facial expressions cannot reveal on screen.• Apply frameworks for transitioning between large pharma and biotech environments, understanding when each setting serves different purposes in executive career development and organisational impact.Snippets• “If you don't feel nervous about a new opportunity, then you're not really taking on something that's upward growth for you.”• “You can't plan everything…You have to leave room for the unexpected, which sometimes can turn out to surprise you in great ways.”• “A lot of focus sometimes is on recruiting the talent. I think the harder part is retaining the talent. And that's where I see not enough investment is made."Timestamps & Topics• 00:14:27 - Three Active Ingredients: People, focus, and bringing everyone along on the leadership journey• 00:17:57 - Early Formation: From first-grade aspiration to molecular biology research with patient tumour samples• 00:22:00 - University Mentorship: The formative impact of Dr. Eric Rubin’s laboratory on career trajectory• 00:38:15 - Clinical to Commercial: Transitioning from oncology practice to pharmaceutical leadership at Merck• 00:45:30 - Leading with Purpose in Biotech: From Oncology Ward to Clinical Consulting with Dr. Nageatte IbrahimResources• Follow Dr. Nageatte Ibrahim on LinkedIn: https://www.linkedin.com/in/nageatte-ibrahim-m-d-56882b8/• Follow Thomas Dove on LinkedIn: https://www.linkedin.com/in/lifesciencesexecutivesearch/Don’t Miss an EpisodeJoin the Active Ingredients podcast community at https://activeingredients.fraserdove.com to receive new episodes delivered the day they drop, invitation to Active Ingredients Live events and more.Remember to tune into our next episode for more inspiring insights. You can also subscribe to the Active Ingredients podcast on Apple Podcasts, Spotify, and other leading podcast platforms.Loved this episode?Share it with your friends, family, or your peers!
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    50 Min.
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