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A Neuroscientific Approach to Menstrual Wellness with Dr Emile Radyte: Exploring Brain-Based Pain and Mood Therapies

In this episode, we welcome Dr Emile Radyte, a Harvard and Oxford-trained neuroscientist specialising in how the brain influences menstrual mood and pain

Dr Radyte discusses her extensive background, including her leadership at Harvard’s emergency medical service and the founding of Lithuania’s largest neuroscience NGO. She is the co-founder of a neuroscience company focused on a brain-first approach to menstrual wellness. The conversation dives deep into the neuroscience behind menstrual pain and mood, explaining how brain circuits, rather than just hormones, regulate these experiences

Dr Radyte elaborates on the innovative non-invasive brain stimulation techniques her team is developing to provide pain relief and mood stabilisation for women with conditions such as PMS, PMDD and endometriosis. She also shares insights on the interplay between hormones, neuroplasticity and brain circuits, as well as ongoing clinical trials and the personalisation of therapeutic protocols for different conditions

Throughout the episode, she highlights the crucial role of self-tracking and personal responsibility in women’s health optimisation

Timestamp

00:00 Introduction and guest welcome
01:05 Understanding the brain-first approach to menstrual health
02:57 Brain circuits and emotional regulation
06:54 Pain perception and sensitivity
09:19 PMS vs PMDD: clinical definitions and differences
12:54 Brain stimulation: a new approach to menstrual health
29:14 Devices and technology for menstrual wellness
35:50 Understanding women’s symptoms and tracking
37:32 Common user mistakes and how to avoid them
41:06 Clinical trials and research initiatives
50:33 User experience with the devices
01:00:43 Curveball questions and personal insights

Resources Mentioned in This Episode

1. Samphire Neurotechnology

• Samphire is a neurotechnology company focused on women’s brain health, particularly hormonal-cycle related symptoms such as:
  • PMS
  • PMDD
  • Menstrual migraines
  • Brain fog
  • Mood and cognitive disruption linked to hormonal changes
• The technology discussed is non-invasive neuromodulation, designed as a drug-free alternative for managing symptoms.

2. Neuroscience & Hormonal Health

• Discussion around how hormonal fluctuations impact the brain, not just reproductive organs.
• Emphasis on the lack of research funding and innovation in women’s neurological health.
• The gap between male-centric medical research models and women’s lived neurological experiences.
  
  

3. Clinical & Regulatory Context

• Samphire’s work within regulated medical frameworks.
• Importance of clinical validation, safety, and evidence-based design for women’s health technology.
• Barriers women face accessing care for cycle-linked neurological symptoms.

4. Lived Experience & Advocacy

• Emile shares the personal motivation behind building Samphire.
• Reframing “normal” suffering around periods and hormones.
• Advocating for women to expect better solutions, not just coping strategies.
  
  
  

Social Media Links

Samphire Website: https://url-shortener.me/4QQW
LinkedIn:https://www.linkedin.com/in/eradyte/

Instagram:https://www.instagram.com/radytee/?hl=

Insta/TikTok: @BiohackingEve
Website: www.BiohackingEve.com