The Brain Twin 🧠: Turning Human Intuition into an AI Layer (with Assaf Horowitz, BrainVivo) Titelbild

The Brain Twin 🧠: Turning Human Intuition into an AI Layer (with Assaf Horowitz, BrainVivo)

The Brain Twin 🧠: Turning Human Intuition into an AI Layer (with Assaf Horowitz, BrainVivo)

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 If you’re building in AI and you think “human cognition” is just more training data, this episode will challenge you.Assaf Horowitz is the Co-Founder & CEO of BrainVivo, a computational neuroscientist working at the edge of sci-fi and enterprise reality: scanning real brains and building “brain twins” — digital models that can predict how a specific expert or audience will feel, value, and decide inside a defined domain. Not a generic model. Not a persona. A measurable cognitive fingerprint.Assaf watched his grandmother—Tova Horowitz, a Holocaust survivor and the smartest person in his world—fade away from Alzheimer’s. The pain wasn’t only losing her. It was watching a lifetime of judgment, perception, and problem-solving disappear with no way to preserve it. That question becomes the company: what if we could capture parts of a mind’s “operating system” — and make it usable?Then it gets wild (and concrete). BrainVivo takes a 45–60 minute MRI session, maps your brain’s wiring (connectome) and activity (fMRI), feeds you controlled stimuli (images, sound, even smell/taste), and trains a “translator” between the world’s inputs and your brain’s internal response. The output is a brain twin that can be tested on new stimuli and used to predict intuition-level reactions.Assaf shares two case studies that make this real: • Cloning expertise: a Michelin-star chef who literally “hears” tomatoes (synesthesia). BrainVivo built a culinary brain twin and hit ~85% accuracy on the gist of his judgments across dozens of dishes—opening the door to scaling founder-level taste and consistency across locations. • Predicting markets & behavior: a project with one of the world’s largest investment banks using digitized audience brains reacting to hourly news headlines, producing a high correlation with the market’s fear index (VIX). • An experiment that beat a gaming company’s internal selection by choosing creatives that dominated click performance.This is a founder conversation about the next AI frontier: not just smarter models, but more human ones.In this episode • What a “brain twin” is—and what it can (and can’t) capture today • Why language is a crude interface for thought, and where LLMs flatten human depth • How MRI + stimuli + an encoding/translation model becomes a usable cognitive agent • Why Assaf believes “NeuroAI” is the next step after LLMs • The ethics: data ownership, anonymization, and why your mind shouldn’t be scrapedCheck out the full episode notes, transcripts, and all links on Substack:👉 https://aggaeus.com/CONNECT WITH ASSAFLinkedInWebsiteCONNECT WITH HAGGAILinkedInFOLLOW AGGAEUSInstagramTikTokYouTubeSPONSORSKardz.Biz – “A business card too good to give away”SUBSCRIBE TO THE PODC ASTApple PodcastsSubstackINQUIRIES💼 Sponsorships/Business: talktous@aggaeus.com🎙 Podcast: DM https://www.instagram.com/aggaeus/ on InstagramSome links may earn affiliate commissions. Offers, terms, and availability may change without noticeAggaeus content is for informational and educational purposes only and should not be considered legal, business, investment, or tax advice. You should conduct your own research and consult qualified professionals before making any decisions.We may feature companies, products, or entities in which Aggaeus, its affiliates, or the author have invested or may invest, or with which they have had, have, or may have a financial, professional, or other relationship.#NeuroAI #DeepTech #Startups #Cognition #AI
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