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St. Ephraim was born within the Roman empire in Mesopotamia around AD 310. He grew up a pious youth and later became a disciple of St. Jacob, a bishop of the city. When his hometown fell to the Persians, he sought retreat as a solitary in a cell on a rocky hill close to the city, along with many other monks. Despite his solitary nature, he became famous as a great teacher, a champion against heresy, as well as an ascetic.

Alban Butler was born in England and worked for a time as a Roman Catholic missionary priest. He was later appointed president of an English seminary in France. His primary literary work, the Lives of the Saints, was published between 1756 and 1759.

St. Alphonsus Liguori (1696 - 1787) was an Italian bishop famous for his moral teaching. Initially, he practiced law, but was drawn to the religious life and became a priest in the Catholic church. He ministered as a missionary to the poor, setting up "evening chapels". He would later form his own congregation and then be appointed as bishop. He wrote many famous sermons, meditations, and ascetical works. His meditations are still used today for the stations of the cross during Lent.