In the clear blue skies above Long Island, two airplanes collide. Tony Stark watches the scene in horror and wishes he had the technology that is almost within his reach - a new hyperintelligent instant control system that could have given the aircraft advance warning. But Stark, an obsessive, increasingly troubled recluse, doesn’t know that his invention has been compromised.
Deep beneath the Empire State University library, a frustrated student finds the lost legacy of ESU's most infamous alumnus. Victor Von Doom's lab notebooks - instructions for how to build a machine that can pierce the veil between Earth and the netherworld - have fallen into the wrong hands. A gate is opened where none should exist, and someone - or something - has invaded our world. The Fantastic Four would be the team to face such a threat...if they could reach one another.
The Fantastic Four - the Thing, the Invisible Woman, the Human Torch, and Mr. Fantastic - have used their powers for the betterment of mankind. For years, the world's top scientists have dreamed of creating a quantum computer, a machine that would be infinitely more powerful than any based on the transistor. Now Reed Richards - Mr. Fantastic - has achieved that dream. He has birthed a device capable of creating the unbreakable cipher, predicting the weather, performing calculations, and retrieving knowledge at heretofore unimagined speeds.
Millionaire industrialist Tony Stark has rejected the lucrative munitions trade that put his company on the map. But he can’t just turn away when the antiterror organization known as S.H.I.E.L.D. asks him for help in its battle against the sinister forces of HYDRA. As the next step in its quest for global domination, the international terrorist cabal is plotting to use cutting-edge technology in a devastating attack on New York City. The source of their advanced weaponry: Stark Industries.
They are the Earth's most revered protectors: Reed Richards, Susan Richards, Ben Grimm, and Johnny Storm - the Fantastic Four. Celebrities around the globe and defenders of mankind, these extraordinary individuals have sworn to confront the perils and challenges facing the modern world and each other, always with unyielding courage, unerring wisdom, and an unshakeable familial bond. But their darkest hour may yet be at hand, as humanity's most frightening threat comes violently from beyond the stars...from the depths of the Negative Zone.