The CNBC Changemakers and Power Players podcast features conversations with leaders shaping the future of business, policy, and culture. In this episode, CNBC's Julia Boorstin sits down with Sarah London, CEO of Centene Corporation — the youngest woman to lead a Fortune 500 company and now at the helm of a $100B+ healthcare giant. London shares how a competitive mindset shaped her leadership, why she believes a CEO should "get all of the blame and none of the credit," and what excites her most about AI in healthcare.

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The CNBC Changemakers and Power Players podcast features candid conversations with leaders shaping business and culture. In this episode, CNBC's Julia Boorstin sits down with Cassandra Morales Thurswell, founder and CEO Kitsch.

Thurswell shares how she turned $30,000 in life savings into a global beauty brand without venture capital or outside investors. She discusses trusting her gut instincts over data and market research, why she deliberately avoided seeking advice from mentors and advisors early on, how she learned business skills through unconventional jobs, and why being underestimated as a young female founder became her advantage.

She also opens up about the pressure and judgment that comes with being a woman building a business, how she's using AI to transform product development and customer engagement, her philosophy on staying true to your own vision rather than following conventional wisdom, and her advice for aspiring entrepreneurs who don't fit the traditional founder mold.

Follow and listen to the "CNBC Changemakers and Power Players" podcast on

Apple and Spotify

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The CNBC Changemakers and Power Players podcast features candid conversations with leaders shaping business and culture. In this episode, CNBC's Julia Boorstin sits down with Jenny Just, co-founder of Peak6 and one of America's self-made female billionaires.

Just started as one of the first women on the Chicago Options Exchange floor — where there wasn't even a women's restroom. In 1997, she co-founded Peak6 with $1.5 million. Today, her fintech empire powers the trading platforms millions use daily, including Robinhood, SoFi, and Betterment. Her firm also employs twice as many female fund managers as the industry benchmark.

Now, Just is on a new mission: teaching one million women the strategic skills of poker to help them succeed in business and life. She shares why getting comfortable with risk and "getting to the table" are essential for the next generation of female leaders — and why poker might be the most underrated tool for building confidence and courage.

Follow and listen to the CNBC Changemakers and Power Players podcast on Apple and Spotify.

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The CNBC Changemakers and Power Players podcast features conversations with leaders shaping the future of business, policy, and culture. In this episode, CNBC's Julia Boorstin speaks with Karen Knudsen--CEO of the Parker Institute for Cancer Immunotherapy and a 2024 CNBC Changemaker--about her professional journey from becoming the first female CEO of the American Cancer Society to leading the charge in turning all cancers into curable diseases. She discusses how the Parker Institute's unique model combines philanthropy with venture capital to accelerate breakthrough therapies and address critical funding gaps in cancer research.

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The CNBC Changemakers and Power Players podcast features conversations with leaders shaping the future of business, policy, and culture. In this episode, CNBC's Julia Boorstin talks with Jacqueline Reses, a 2024 CNBC Changemaker and the co-founder, chair & CEO of Lead Bank. Reses discusses her ambitions to transform fintech, managing decisively, creating critical lifelines for small businesses during the pandemic, the role of DEI, and invaluable business lessons from growing up on the Jersey Shore.

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The CNBC Changemakers and Power Players podcast features conversations with leaders shaping the future of business, policy, and culture. In this episode, CNBC's Julia Boorstin talks with Caryn Seidman-Becker, a 2025 CNBC Changemaker and the CEO of Clear. They discuss how Caryn transformed Clear from a bankrupt travel company into a secure identity platform serving more than 30 million members, expanding beyond airports into enterprise partnerships with DocuSign and LinkedIn, combating AI-driven deepfakes and identity fraud, and Caryn's philosophy of being "indefatigable" in pursuing opportunities that seemed impossible years ago.

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The CNBC Changemakers and Power Players podcast features conversations with leaders shaping the future of business, policy, and culture. In this episode, CNBC's Julia Boorstin talks with 2025 CNBC Changemakers Michal and Merav Mor about their journey from medical school rejection to building Lumen, a game-changing metabolism-tracking device with over 350,000 users. The twin sisters discuss how their athletic background competing in Ironman races shaped their business resilience and their unique approach to family business dynamics.

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The CNBC Changemakers and Power Players podcast features conversations with leaders shaping the future of business, policy, and culture. In this episode, CNBC's Julia Boorstin talks with Arati Prabhakar, a former White House science and technology advisor and former head of DARPA, the government agency behind many breakthrough technologies.

Prabhakar is a first-generation immigrant and the first woman to earn a PhD in applied physics from Caltech. Over her career, she has helped shape major decisions around semiconductors, early mRNA research, artificial intelligence, and national security. She shares her non-linear career path, what it means to lead responsibly in powerful technologies, and why investing in public research — with strong ethical guardrails for AI — matters for the country's future.

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