In 1969 the US Air Force issued a statement that read‚ "No UFO reported, investigated, and evaluated by the Air Force was ever an indication of threat to our national security." This statement has been proven untrue by the testimony of many military officers and airmen and documentation of incidents involving UFOs and nuclear weapons, testimonies of which the US Air Force was fully aware. UAPs and the Nuclear Puzzle details many of these testimonies, some for the first time.

As partial justification for its position, the Air Force cites a University of Colorado study that was contracted and paid for by federal funds. UAPs and the Nuclear Puzzle reveals how this study was actually just another part of the plan to cover up the reality of the UFO phenomenon. This book reveals evidence that the investigators for the Colorado study knew about the UFO-related missile shutdown incidents but did not investigate them or include them in their final report.

As stated by Robert Salas: "To date, many former or retired US Air Force personnel—once trusted to operate or guard weapons of mass destruction—have come forward and revealed ongoing UFO surveillance of, and occasional interference with, our nuclear weapons. The entire body of these factual accounts alters the historical perspective on the nuclear arms race."