She is asked live on air about the sensational case of Hannah Starr, who has vanished and is presumed dead. Moments later during the same broadcast, she receives a startling call-in from a former psychiatric patient of Benton Wesley's.

When she returns after the show to the apartment where she and Benton live, she finds a suspicious package - possibly a bomb - waiting for her at the front desk. Soon the apparent threat on Scarpetta's life finds her embroiled in a deadly plot that includes a famous actor accused of an unthinkable sex crime and the disappearance of a beautiful millionairess with whom Lucy seems to have shared a secret past....