Topanga Canyon is home to two couples on a collision course. Los Angeles liberals Delaney and Kyra Mossbacker lead an ordered, sushi-and-recycling existence in a newly gated hilltop community: He is a sensitive nature writer, she an obsessive realtor. Mexican illegals Candido and America Rincon desperately cling to their vision of the American Dream as they fight off starvation in a makeshift camp deep in the ravine.

It is 1994, and in the desert near Tillman, Arizona, 40 miles from Tucson, a grand experiment involving the future of humanity is underway. As climate change threatens the Earth, eight scientists, four men and four women dubbed the Terranauts, have been selected to live under glass in E2, a prototype of a possible off-Earth colony. Their sealed three-acre compound comprises five biomes - rain forest, savanna, desert, ocean, and marsh - and enough wildlife, water, and vegetation to sustain them.

Alma Boyd Takesue is a National Park Service biologist who is spearheading the efforts to save the Channel Islands’ endangered native creatures from invasive species like rats and feral pigs, which, in her view, must be eliminated. Her antagonist, Dave LaJoy, is a dreadlocked local businessman who, along with his lover, the folksinger Anise Reed, is fiercely opposed to the killing of any species whatsoever and will go to any lengths to subvert the plans of Alma and her colleagues.

Set in contemporary Northern California, The Harder They Come explores the volatile connections between three damaged people - an aging ex-marine and Vietnam veteran, his psychologically unstable son, and the son's paranoid, much older lover - as they careen toward an explosive confrontation.

Told through the experiences of the four women who loved him, this imaginative account of Frank Lloyd Wright's raucous life blazes with Boyle's trademark wit and invention. Boyle's protean voice captures these very different women and, in doing so, creates a masterful ode to the creative life in all its complexity and grandeur.