Hustling men for their money has always come easy for Tasha. Hailing from New York and raised by a junkie mother, she had to learn early how to use her beauty to her advantage. Tasha thinks she's seen it all on the streets of New York, but when she follows a childhood friend to the little city of Flint, Michigan, she realizes that sometimes the smallest cities breed the grimiest of individuals.
When Tasha and her friends link up with Manolo, one of Flint's known stick-up kids, they take the hustlers of Flint for all they're worth. Any man who falls for a pretty face is a target, and under the guidance of Manolo, the girls quickly learn the game of manipulation and deceit. They become known as the Manolo Mamis, and their skills gain them thousands of dollars in no time.
Tasha is living the life of the young and fly, but when tragedy strikes and the stakes are raised, she has to choose between loyalty and self-sacrifice. When the only man she's ever loved becomes her target, will she decide to save him, or will she remain loyal to the Manolo Mamis?