Why can one person drink a flat white at 3pm and sleep soundly, while another lies awake until midnight? Why does one glass of wine turn some people bright red? A lot of it comes down to your genes.

In this solo episode, I break down the caffeine and alcohol genes I look at in my clients' myDNA reports, what your results can and can't tell you, and the simple changes that follow.

In this episode:
- How CYP1A2 shapes how long caffeine hangs around, and why your cut-off time matters
- What the research shows about caffeine, genetics and athletic performance
- ADORA2A, and why some people feel caffeine far more strongly than others
- The ALDH2 variant behind the alcohol flush, and why it matters for more than a red face
- The ripple effects: vitamin B1, REM sleep, APOE, and the unfiltered coffee and cholesterol link
- Why genetics loads the gun, and environment pulls the trigger

Find out what your genes say with my DNA Blueprint Package, available in New Zealand, Australia and the USA:
genetics, DNA test, nutrigenomics, myDNA, caffeine, coffee, alcohol, alcohol flush, red face after drinking, ALDH2, CYP1A2, ADORA2A, APOE, caffeine metabolism, sleep, REM sleep, thiamine, vitamin B1, cholesterol, longevity, personalised health, functional medicine, Lisa Tamati, Pushing the Limits

More on thiamine: my full interview with Elliot Overton
https://www.youtube.com/watch?v=8qwb_XmDqqk

Chapters:
0:00 Same coffee, different genes
0:18 Why blanket health advice fails
1:00 Your caffeine gene: CYP1A2
2:48 Caffeine, sleep and the cut-off
3:27 Caffeine and athletic performance
4:34 ADORA2A: how strongly you feel caffeine
5:35 Alcohol and the ALDH2 gene
7:45 Ripple effects: B1, sleep, APOE and coffee
10:25 Genes load the gun
11:14 Your next step

Educational content only. Genetics shows tendencies and priorities, not diagnoses.